DSM-III-R NICOTINE DEPENDENCE IN YOUNG-ADULTS - PREVALENCE, CORRELATES AND ASSOCIATED PSYCHIATRIC-DISORDERS
DSM-III-R NICOTINE DEPENDENCE IN YOUNG-ADULTS - PREVALENCE, CORRELATES AND ASSOCIATED PSYCHIATRIC-DISORDERS
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DOI：
10.1111/j.1360-0443.1994.tb00960.x
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发表时间：
1994-06-01
期刊：
影响因子：
6
通讯作者：
ANDRESKI, P
中科院分区：
文献类型：
--
作者：
BRESLAU, N;KILBEY, MM;ANDRESKI, P
我们描述了尼古丁依赖的流行病学及其与其他物质使用和精神疾病的关系。数据来自于一个随机抽样的年轻人，年龄在21-30岁之间，来自密歇根州底特律大都会区。采用NIMH诊断访谈表确定DSM-III-R障碍。终生尼古丁依赖患病率为20%。在白人、受教育程度低的人和分居或离婚的人中，这一比例更高。与不依赖吸烟者和不吸烟者的总和相比，有尼古丁依赖的男性和女性患酒精和非法药物障碍、严重抑郁症和一种或多种焦虑症的几率显著增加。在吸烟者中，依赖者一生中除大麻以外的非法药物障碍、严重抑郁和任何焦虑障碍的患病率明显高于非依赖者。重度抑郁症与尼古丁依赖密切相关，这种关联部分可以用神经质来解释。这一发现表明，神经质的人格特征可能是导致重度抑郁症和尼古丁依赖的共同因素。
We describe the epidemiology of nicotine dependence and its association with other substance use and PSYChiatric disorders. Data came from a random sample of young adults, 21-30 years of age, in the Detroit, Michigan metropolitan area. The NIMH Diagnostic Interview Schedule was used to ascertain DSM-III-R disorders. Lifetime prevalence of nicotine dependence was 20%. Higher rates were observed in whites, persons with low education and persons who were separated or divorced. Males and females with nicotine dependence had significantly increased odds for alcohol and illicit drug disorders, major depression and one or more anxiety disorder, as compared to non-dependent smokers and non-smokers combined. Among smokers, lifetime Prevalence of illicit drug disorders other than marijuana alone, major depression and any anxiety disorder were significantly higher in dependent than non-dependent people. Major depression was associated specifically with nicotine dependence, an association explained in part by neuroticism. This finding suggests that the personality trait of neuroticism might constitute a common predisposition for major depression and nicotine dependence.