A COMPARISON OF RISK-FACTORS AND PROGNOSIS FOR TRANSIENT ISCHEMIC ATTACKS AND MINOR ISCHEMIC STROKES - THE OXFORDSHIRE COMMUNITY STROKE PROJECT
A COMPARISON OF RISK-FACTORS AND PROGNOSIS FOR TRANSIENT ISCHEMIC ATTACKS AND MINOR ISCHEMIC STROKES - THE OXFORDSHIRE COMMUNITY STROKE PROJECT
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DOI：
10.1161/01.str.20.11.1494
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发表时间：
1989-11-01
期刊：
影响因子：
8.3
通讯作者：
WARLOW, CP
中科院分区：
文献类型：
--
作者：
DENNIS, MS;BAMFORD, JM;WARLOW, CP
在一项以社区为基础的短暂性脑缺血发作和卒中的研究中，我们确定了184例短暂性脑缺血发作和213例首次轻微缺血性卒中。年龄、性别、并存血管疾病的患病率和危险因素的比较显示两组之间没有重大差异。轻微缺血性卒中患者进一步卒中和进一步卒中和/或死亡的风险更大，尽管仅后者差异显著。短暂性脑缺血发作患者中一过性黑蒙患者的预后较好，这在很大程度上可以解释预后的明显差异。尽管出于某种目的，区分短暂性脑缺血发作和轻微缺血性卒中可能是有用的，但这两组的相似性表明，在许多情况下，包括在中风二级预防治疗的临床试验中，可以省去对它们的任意区分。
In a community-based study of transient ischemic attack and stroke, we identified 184 cases of transient ischemic attack and 213 cases of first-ever minor ischemic stroke. A comparison of age, sex, and prevalence of coexistent vascular diseases and risk factors revealed no major differences between the two groups. The risk of further stroke and of further stroke and/or death was greater in patients with minor ischemic stroke although the difference was significant only for the latter. The apparent differences in prognosis could largely be accounted for by the favorable prognosis of patients with amaurosis fugax among those with transient ischemic attack. Although for some purpose it may be useful to distinguish transient ischemic attacks from minor ischemic strokes, the similarity of the two groups suggests that in many situations, including in clinical trials of treatments for the secondary prevention of strokes, the arbitrary distinction between them could be dispensed with.