The PTSim and TOPAS Projects, Bringing Geant4 to the Particle Therapy Clinic (Selected Papers of the Joint International Conference of Supercomputing in Nuclear Applications and Monte Carlo : SNA + MC 2010)

The PTSim and TOPAS Projects, Bringing Geant4 to the Particle Therapy Clinic (Selected Papers of the Joint International Conference of Supercomputing in Nuclear Applications and Monte Carlo : SNA + MC 2010)
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PTSim 和 TOPAS 项目,将 Geant4 引入粒子治疗诊所(核应用超级计算和蒙特卡洛国际联合会议论文选集:SNA MC 2010)

DOI:
10.15669/pnst.2.912
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发表时间:
2011
期刊:
Progress in nuclear science and technology
影响因子:
--
通讯作者:
B. Faddegon
B. Faddegon
中科院分区:
--
文献类型:
--
作者:
T. Akagi;T. Aso;B. Faddegon

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虽然Geant4模拟工具包已经在粒子治疗领域被广泛接受,目前参与这种创新癌症治疗方法的大多数主要中心都进行了研究和临床使用,但事实证明,这些应用所需的高水平Geant4专业知识对用户来说是一个严重的障碍。日本的PTSim合作和美国的Topas合作包装和扩展了Geant4工具包,以满足这一关键社区的需求。PTSim提供了一个通用平台来对日本的三个质子和离子治疗设施以及其他国家的三个设施进行建模,使非Geant4专家的用户能够准确而高效地对这些预置配置中的任何一个运行Geant4模拟。TOPAS项目建立在韩国NCC MGH(世界上第一个质子治疗系统的所在地)和其他地方丰富的质子治疗应用历史的基础上,旨在进一步提高灵活性,允许任何粒子治疗临床医生或研究人员仍然可以模拟他们自己的真实或设想的设施,而不需要Geant4专家。我们描述了这些项目,它们的设计如何弥合灵活性和易用性之间的差距,它们贡献了哪些缺少的关键软件组件,以及这两个项目可能如何共同发展。
Though the Geant4 Simulation Toolkit has been widely accepted in the particle therapy community, with research and clinical use at most of the major centers currently involved in this innovative approach to cancer treatment, the high level of Geant4 expertise required for these applications has proven a serious barrier for users. The PTSim collaboration in Japan and the TOPAS collaboration in the United States wrap and extend the Geant4 toolkit to meet the needs of this critical community. PTSim has provided a common platform to model three Japanese proton and ion therapy facilities plus three more in other countries, allowing users who are not Geant4 experts to accurately and efficiently run Geant4 simulations for any of these pre-built configurations. Building on a rich history of proton therapy applications at MGH (site of the world's first proton therapy system), NCC Korea, and elsewhere, the TOPAS project aims to take flexibility further, allowing any particle therapy clinician or researcher to Geant4-simulate their own real or envisioned facility still without requiring a Geant4 expert. We describe these projects, how their designs bridge the gap between flexibility and ease of use, what key missing software components they have contributed and how the two projects may evolve together.
DOI: 10.1118/1.2715481
发表时间: 2007-04-01
期刊: MEDICAL PHYSICS
影响因子: 3.8
作者:
Jiang, Hongyu;Seco, Joao;Paganetti, Harald
通讯作者: Paganetti, Harald