A neural link between feeling and hearing.
A neural link between feeling and hearing.
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DOI：
10.1093/cercor/bhs166
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发表时间：
2013-07
期刊：
影响因子：
3.7
通讯作者：
T. Ro;T. Ellmore;M. Beauchamp
中科院分区：
文献类型：
--
作者：
T. Ro;T. Ellmore;M. Beauchamp
听觉和感觉都依赖于将物理事件转换为基于频率的神经代码，这表明听觉系统可能与躯体感觉系统密切相关。在这里，我们提供的证据表明，听觉和躯体感觉的神经基板是解剖学上的联系。使用扩散张量成像与确定性和概率纤维束成像来测量白色物质的连接，我们发现，有广泛的同侧之间的初级听觉皮层和初级和次级躯体感觉区域在人类大脑皮层的连接。我们进一步表明，这些跨模态的连接被夸大的听觉和次级躯体感觉皮层的患者（SR）与获得性触觉联觉，其中声音单独产生身体感觉的病变半球。这些结果提供了一个解剖学基础的听觉和体感之间的多感官的相互作用，并建议这些区域之间的串扰可以解释为什么有些声音，如指甲尖叫下来的黑板或一个可听见的蚊子，可以诱导触摸的感觉，特别是对患者SR的contralesional身体表面。
Hearing and feeling both rely upon the transduction of physical events into frequency-based neural codes, suggesting that the auditory system may be intimately related to the somatosensory system. Here, we provide evidence that the neural substrates for audition and somatosensation are anatomically linked. Using diffusion tensor imaging with both deterministic and probabilistic tractography to measure white matter connectivity, we show that there are extensive ipsilateral connections between the primary auditory cortex and the primary and secondary somatosensory regions in the human cerebral cortex. We further show that these cross-modal connections are exaggerated between the auditory and secondary somatosensory cortex in the lesioned hemisphere of a patient (SR) with acquired auditory-tactile synesthesia, in whom sounds alone produce bodily sensations. These results provide an anatomical basis for multisensory interactions between audition and somatosensation and suggest that cross-talk between these regions may explain why some sounds, such as nails screeching down a chalkboard or an audible mosquito, can induce feelings of touch, especially on the contralesional body surface of patient SR.