Pulsatile blood flow in the polypoidal choroidal vasculopathy
Pulsatile blood flow in the polypoidal choroidal vasculopathy
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DOI：
10.1016/j.ophtha.2005.03.017
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发表时间：
2005-08-01
期刊：
影响因子：
13.7
通讯作者：
Sakamoto, T
中科院分区：
文献类型：
--
作者：
Okubo, A;Ito, M;Sakamoto, T
目的：描述息肉状脉络膜血管病变（PCV）中搏动性息肉状血管的患者。设计：回顾性观察病例系列。参与者：74例PCV患者的84只眼。方法：回顾1998年至2004年鹿儿岛大学医院诊断为PCV的患者的病历。主要结果测量：吲哚菁绿绿色血管造影（ICGA）显示搏动性息肉状血管（PV）。4只眼在首次诊断PCV当天显示搏动性PV，另外3只眼在随访期间显示PV搏动性运动。在ICGA上观察到两种搏动运动模式：（1）脉络膜血管口径的节律性变化（口径变化模式）和（2）曲折且相对狭窄的脉络膜血管中的搏动性血流（搏动性血流模式）。两种模式的脉动PV都出现在ICGA的早期帧中，其中一些甚至在ICG染料注射后的前15分钟内也可观察到。搏动性运动消失自发未经治疗的一些患者，在ICGA上检测到的搏动性PV的时间是有限的，在每个patient.Conclusions：我们报告的搏动性PV PCV的特点。这是一个独特的和重要的特点，还没有与任何其他脉络膜视网膜疾病的报告，并可能提供一个线索，以了解PCV的发病机制。
Objective: To describe patients with pulsatile polypoidal vessels in polypoidal choroidal vasculopathy (PCV).Design: Retrospective, observational case series.Participants: Eighty-four eyes of 74 patients with PCV.Methods: The medical records of patients diagnosed with PCV between 1998 and 2004 at Kagoshima University Hospital were reviewed.Main Outcome Measures: A pulsatile polypoidal vessel (PV) on indocyanine green angiography (ICGA).Results: Seven of 74 patients (9.5%) had PVs in the macula. Four eyes revealed pulsatile PVs on the day the diagnosis of PCV was first made, and PVs in the other 3 eyes showed pulsatile movement during the follow-up period. Two patterns of pulsatile movement were observed on ICGA: (1) a rhythmic variation in the caliber of a choroidal vessel (caliber variation pattern) and (2) a pulsatile blood flow in a tortuous and relatively narrow choroidal vessel (pulsatile blood flow pattern). Both patterns of pulsatile PVs appeared in the early frames of the ICGA, and some of them were observable even during the first 15 minutes after the ICG dye injection. The pulsatile movement disappeared spontaneously without treatment in some patients, and the period in which pulsatile PVs was detectable on ICGA was limited in each patient.Conclusions: We report the features of pulsatile PV in PCV. It is a unique and important characteristic that has not been reported with any other chorioretinal diseases and may provide a clue to understanding the pathogenesis of PCV.