The 20 item oral mucositis index: reliability and validity in bone marrow and stem cell transplant patients.
The 20 item oral mucositis index: reliability and validity in bone marrow and stem cell transplant patients.
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20项口腔粘膜炎指数：骨髓和干细胞移植患者的信度和效度。
DOI：
10.1081/cnv-120005902
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发表时间：
2002
影响因子：
2.4
通讯作者：
Schubert,MarkM
中科院分区：
文献类型：
--
作者：
McGuire,DeborahB;Peterson,DouglasE;Muller,Susan;Owen,DonnaC;Slemmons,MarinaF;Schubert,MarkM
在测试粘膜炎的新治疗策略时，接受骨髓和干细胞移植的癌症患者的口腔并发症的精确定量是必不可少的。使用133名成人移植患者，作者评价了20项口腔粘膜炎指数（OMI），改编自34项OMI，以方便非牙科健康专业人员使用。OMI-20由9个测量红斑的项目、9个测量溃疡的项目、1个测量萎缩的项目和1个测量水肿的项目组成;所有项目的评分范围为0=无至3=重度，总分为0-60。测量红斑和溃疡的两组九个项目也可以分别相加，以产生范围为0至27的子量表评分。结果表明，内部一致性，重测，评分员之间的信度，和强有力的证据结构效度。如果临床检查者有适当的培训和经验，OMI-20可以在临床研究中用作可靠，有效和可量化的粘膜炎指标。
Precise quantification of oral complications in cancer patients receiving bone marrow and stem cell transplantation is essential when testing new treatment strategies for mucositis. Using 133 adult transplant patients, the authors evaluated the 20 item oral mucositis index (OMI), adapted from the 34 item OMI, to facilitate use by nondental health professionals. The OMI-20 consists of nine items measuring erythema, nine measuring ulceration, one measuring atrophy, and one measuring edema; all are scored from 0=none to 3=severe and summed for a total possible score of 0–60. The two sets of nine items measuring erythema and ulceration can also be summed separately to produce subscale scores ranging from 0 to 27. Results demonstrated internal consistency, test–retest, and inter-rater reliability, and strong evidence of construct validity. Provided that clinical examiners have appropriate training and experience, the OMI-20 can be used as a reliable, valid, and quantifiable measure of mucositis in clinical research.