La cuerda dulce--a tolerability and acceptability study of a novel approach to specimen collection for diagnosis of paediatric pulmonary tuberculosis.
La cuerda dulce--a tolerability and acceptability study of a novel approach to specimen collection for diagnosis of paediatric pulmonary tuberculosis.
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DOI：
10.1186/1471-2334-6-67
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发表时间：
2006-04-04
影响因子：
3.7
通讯作者：
Moore DA
中科院分区：
文献类型：
--
作者：
Chow F;Espiritu N;Gilman RH;Gutierrez R;Lopez S;Escombe AR;Evans CA;Moore DA
最近的数据证明了弦线测试在诊断成人痰稀 HIV 相关结核病方面的实用性。我们假设，如果儿童耐受性良好，这个简单的工具可能会为儿科结核病诊断带来突破。因此，这项研究是在秘鲁利马国家多斯德梅奥医院的儿科服务部门进行的，目的是确定儿童结核病嫌疑人、其父母和护理人员对线测试的耐受性和可接受性。 22 名接受结核病调查、年龄在 3-14 岁（中位数为 8 岁）的儿科受试者被邀请接受 2 次线测试（每次休息时间为 4 小时）。使用主观和客观疼痛和不适评定量表来评估受试者、家长和主治护士的感受。年仅 4 岁的患者对手术的耐受性非常好，84% 的患者愿意接受第二次手术。根据视觉模拟评级和客观指标判断，吞咽和取绳时的峰值不适程度较轻（最大可能分数的 30%）且短暂。家长/孩子和客观/主观评分的良好一致性增强了这些发现的有效性。对于大多数年仅 4 岁的儿童结核病嫌疑人来说，绳索测试具有良好的耐受性和可实现性。现在需要进行正式的前瞻性儿科疗效研究。
Recent data demonstrate the utility of the string test for the diagnosis of sputum-scarce HIV-associated TB in adults. We hypothesized that, if well-tolerated by children, this simple tool might offer a breakthrough in paediatric TB diagnosis. Thus the objective of this study, undertaken in the paediatric service of the Hospital Nacional Dos de Mayo, Lima, Perú, was to determine the tolerability and acceptability of the string test to paediatric TB suspects, their parents and nursing staff. 22 paediatric subjects aged 3–14 years (median 8) under investigation for TB were invited to undergo 2 string tests (four-hour downtime each). Subjective and objective pain and discomfort rating scales were used to assess the perception of the subject, parent and attending nurse. Patients as young as 4 years tolerated the procedure extremely well with 84% willing to undergo a second procedure. Peak discomfort at the time of swallowing and of string retrieval was mild (30% of maximum possible score) and brief as judged by visual analogue ratings and objective indicators. Good concordance of parent/child and objective/subjective ratings strengthened the validity of these findings. The string test is well tolerated and achievable for most paediatric TB suspects as young as 4 years. A formal prospective paediatric efficacy study is now needed.
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影响因子：
9.4
作者：
Moore, DAJ;Mendoza, D;Serpa, J
通讯作者：
Serpa, J
影响因子：
168.9
作者：
Franchi, LM;Cama, RI;Sheen, P
通讯作者：
Sheen, P
DOI：
10.4269/ajtmh.1970.19.349
发表时间：
1970-01-01
影响因子：
3.3
作者：
BEAL, CB;UNIV, MONTRE;HUGHES, JM
通讯作者：
HUGHES, JM
DOI：
10.1001/archpedi.1980.02130200045014
发表时间：
1980-01-01
影响因子：
--
作者：
LIEBMAN, WM;ROSENTHAL, P
通讯作者：
ROSENTHAL, P
影响因子：
3.3
作者：
van Rheenen, P
通讯作者：
van Rheenen, P