THE KERATITIS, ICHTHYOSIS, AND DEAFNESS (KID) SYNDROME
THE KERATITIS, ICHTHYOSIS, AND DEAFNESS (KID) SYNDROME
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DOI：
10.1001/archderm.117.5.285
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发表时间：
1981-01-01
影响因子：
--
通讯作者：
NORINS, AL
中科院分区：
文献类型：
--
作者：
SKINNER, BA;GREIST, MC;NORINS, AL
一名患有鱼鳞病、角膜炎、耳聋和顽固性皮肤细菌和真菌感染的患者先前被描述为患有遗传性少汗性外胚层发育不良。文献中描述的类似受影响的患者具有以下共同特征：独特的鱼鳞病，其特征是细小的干鳞、毛囊角化过度棘以及手掌和足底的网状角化过度图案；导致明显视力障碍的血管化角膜炎；和神经感觉性耳聋。一半受影响的患者还表现出频繁、严重的皮肤感染。 KID 综合征这个名称是为了强调该综合征的特征：角膜炎、鱼鳞病和耳聋。
A patient with ichthyosis, keratitis, deafness and recalcitrant cutaneous bacterial and fungal infections previously described as having hereditary hypohidrotic ectodermal dysplasia was described. Similarly affected patients described in the literature had the following features in common: a distinctive ichythosis characterized by a fine dry scale, follicular hyperkeratotic spines and a reticulated pattern of hyperkeratosis on the palms and soles; a vascularizing keratitis that resulted in notable visual impairment; and neurosensory deafness. Half of the affected patients also displayed frequent, severe cutaneous infections. The name the KID syndrome was suggested to emphasize the characteristic features of the syndrome: keratitis, ichthyosis and deafness.