Home dampness and respiratory health status in European children
Home dampness and respiratory health status in European children
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DOI：
10.1046/j.1365-2222.1998.00322.x
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发表时间：
1998-10-01
影响因子：
6.1
通讯作者：
Roemer, W
中科院分区：
文献类型：
--
作者：
Andriessen, JW;Brunekreef, B;Roemer, W
背景在以往的研究中，生活在潮湿的家庭中与呼吸系统健康受损有关，但大多数研究都缺乏关于肺功能变异性和特应性的客观数据。（污染对欧洲哮喘儿童的影响）被用来研究家庭湿度和峰值流速（PEF）变异性之间的关系，在观察期间呼吸道症状和缓解药物使用的频率。方法根据对哮喘和慢性咳嗽症状的问题的积极回答，用筛选问卷选择儿童。指导儿童在2个月内每天两次使用Miniwright PEF测量仪进行PEF测量。父母记录孩子的呼吸道症状和药物使用情况。关于人口统计学和住房特征的数据来自父母管理的问卷。作为家庭潮湿的指标，报告使用了潮湿污渍和霉菌。儿童接受皮肤点刺试验以检查是否有特应性。来自10个不同国家13个中心的1614名儿童的数据可供分析。线性回归模型和患病率比率被用来调查家庭潮湿和PEF变异和咳嗽，痰，下呼吸道和上呼吸道症状和支气管扩张剂的使用期间患病率之间的关联。咳嗽和上呼吸道症状的期间患病率显着较高的儿童生活在房子里报告的模具，与'干' homes.Conclusions这些结果表明，自报模具在家中与客观以及主观标记的气道不稳定的欧洲儿童慢性呼吸道症状。
Background Living in a damp home has been associated with impaired respiratory health in previous studies, but objective data on lung function variability and atopy have been lacking from most studies.Objectives Data collected in the winter of 1993-1994 in the framework of the PEACE study (Pollution Effects on Asthmatic Children in Europe) were used to study the association between home dampness and Peak Flow (PEF) variability, frequency of respiratory symptoms and relief medication use during the period of observation.Methods Children were selected with a screening questionnaire on the basis of positive answers to questions on symptoms of asthma and chronic cough. Children were instructed to perform PEF measurements with Miniwright PEF meters twice daily over a period of 2 months. Parents kept diaries on respiratory symptoms and medication use of their children. Data on demographic and housing characteristics were derived from a parent-administered questionnaire. As indicators for home dampness reported moisture stains and moulds were used. Children were tested for atopy with skin-prick tests. Data from 1614 children from 13 centres in 10 different countries were available for analysis. Linear regression models and prevalence rate ratios were used to investigate the association between home dampness and PEF variability and the period prevalence of cough, phlegm, lower and upper respiratory symptoms and bronchodilator use.Results In atopic children, PEF variability was positively related to self-reported moulds but not to moisture stains. The period prevalence of cough and upper respiratory symptoms was significantly higher in children living in houses with reported moulds, compared with 'dry' homes.Conclusions These results show that self-reported moulds in homes are associated with objective as well as subjective markers of airway lability in European children with chronic respiratory symptoms.