Giant cell tumor of tendon sheath and pigmented villonodular synovitis: an ultrastructural study.
Giant cell tumor of tendon sheath and pigmented villonodular synovitis: an ultrastructural study.
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腱鞘巨细胞瘤和色素沉着绒毛结节性滑膜炎：超微结构研究。
DOI：
10.1093/ajcp/69.1.6
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发表时间：
1978
影响因子：
3.5
通讯作者：
J. Goellner
中科院分区：
文献类型：
--
作者：
A. Alguacil‐Garcia;K. Unni;J. Goellner
对5例腱鞘巨细胞瘤和1例色素沉着绒毛结节性滑膜炎的超微结构进行了观察。巨细胞瘤主要由A、B型滑膜细胞组成。还存在具有密度的胞浆内细丝的成纤维细胞（肌成纤维细胞）以及“单核细胞”和“淋巴细胞”细胞。巨细胞似乎是由A型滑膜细胞融合而成，而泡沫细胞则是由A、B细胞融合而成。巨细胞瘤和色素性滑膜炎都被认为是滑膜细胞的反应性和边缘性增生性病变。
The ultrastructures of five examples of giant cell tumors of the tendon sheath and one example of pigmented villonodular synovitis were studied. The giant cell tumors were composed mostly of A and B types of synovial cells. Also present were fibroblastic cells with intracytoplasmic filaments with densities (myofibroblasts) as well as "monocytic" and "lymphocytic" cells. The giant cells seemingly were derived from the fusion of synovial cells of A type, whereas foam cells were derived from both A and B cells. Both the giant cell tumors and the pigmented synovitis are considered to be reactive and borderline proliferative lesions of the synovial cells.