Preparation and application of hydrophilic monolithic columns
Preparation and application of hydrophilic monolithic columns
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DOI：
10.1016/j.chroma.2011.02.024
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发表时间：
2011-04-29
影响因子：
4.1
通讯作者：
Liu, Zhenghua
中科院分区：
文献类型：
--
作者：
Jiang, Zhengjin;Smith, Norman William;Liu, Zhenghua
亲水作用色谱（HILIC）近年来受到越来越多的关注。在HILIC分离机理、柱技术和应用等方面进行了大量的研究。亲水性整体柱由于其良好的渗透性、低的传质阻力和易于在毛细管内制备，代表了新型HILIC柱技术的发展趋势。本文综述了近十年来HILIC整体柱的制备和应用。对各种亲水性整体固定相的分离机理进行了综述。(C)2011 Elsevier B.V.保留所有权利。
Hydrophilic interaction chromatography (HILIC) has experienced increasing attention in recent years. Much research has been carried out in the area of HILIC separation mechanisms, column techniques and applications. Because of their good permeability, low resistance to mass transfer and easy preparation within capillaries, hydrophilic monolithic columns represent a trend among novel HILIC column techniques. This review attempts to present an overview of the preparation and applications of HILIC monolithic columns carried out in the past decade. The separation mechanism of various hydrophilic monolithic stationary phases is also reviewed. (C) 2011 Elsevier B.V. All rights reserved.