Control of telomerase action at human telomeres.
Control of telomerase action at human telomeres.
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DOI：
10.1038/nsmb.3083
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发表时间：
2015-11
影响因子：
16.8
通讯作者：
Collins K
中科院分区：
文献类型：
--
作者：
Hockemeyer D;Collins K
Recent progress has greatly increased the understanding of telomere-bound shelterin proteins and the telomerase holoenzyme, predominantly as separate complexes. Pioneering studies have begun to investigate the requirements for shelterin-telomerase interaction. From this vantage point, focusing on human cells, we review and discuss models for how telomerase and shelterin subunits coordinate to achieve balanced telomere-length homeostasis.
