Nocturia indicates a poor health status and increases mortality in male patients with type 2 diabetes mellitus
Nocturia indicates a poor health status and increases mortality in male patients with type 2 diabetes mellitus
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夜尿表明男性 2 型糖尿病患者健康状况不佳并增加死亡率
DOI：
10.1007/s11255-016-1310-3
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发表时间：
2016
影响因子：
2
通讯作者：
Y. Chuang
中科院分区：
文献类型：
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作者：
Hui;Min;H. Wang;Rue‐Tsuan Liu;Y. Chuang
ObjectivesTo探讨男性2型糖尿病患者勃起功能障碍、雄激素缺乏、膀胱过度活动症和全身性疾病与排尿功能障碍的关系。方法采用自填式问卷，包括男性2型糖尿病患者膀胱过度活动症症状评分和性健康调查表。夜尿症和重度尿失禁分别定义为每晚排尿次数≥2或≥3次。患者的特点和糖尿病相关的并发症，以风险的pasturia.ResultsOf 632连续科目，56.0和24.2%的报告有pasturia和严重pasturia，分别。在调整年龄、糖尿病病程和膀胱过度活动症后，勃起功能障碍、中风、高血压和较高血清肌酸酐水平的存在与夜尿和严重夜尿有关。睾酮水平最低的四分位数（2.21 ± 0.51 ng/mL）患者的尿失禁患病率（65.1%）和重度尿失禁患病率（32.9%）高于其他三个四分位数的总和。严重的糖尿病患者的死亡率比其他组高3倍后3.5年follow-up.ConclusionsThe存在的糖尿病与勃起功能障碍，全身血管事件，较高的死亡率，并表示健康状况不佳的男性2型糖尿病。
ObjectivesTo investigate the association between nocturia and erectile dysfunction, androgen deficiency, overactive bladder and systemic diseases in men with type 2 diabetic mellitus.MethodsA self-administered questionnaire containing overactive bladder symptom score and sexual health inventory for men was obtained from subjects with type 2 diabetic mellitus. Nocturia and severe nocturia were defined as rising ≥2 or ≥3 per night to void, respectively. Patient characteristics and diabetes-related complications to risk of nocturia were evaluated.ResultsOf 632 consecutive subjects, 56.0 and 24.2 % reported having nocturia and severe nocturia, respectively. After adjustment of age, diabetic mellitus duration, and overactive bladder, the presence of erectile dysfunction, stroke, hypertension, and higher serum creatinine level was associated with nocturia and severe nocturia. The patients with the lowest quartile of testosterone level (2.21 ± 0.51 ng/mL) had higher prevalence of nocturia (65.1 %) and severe nocturia (32.9 %) than the sum of the other three quartiles. The patients with severe nocturia had threefold higher mortality than the other group after 3.5-year follow-up.ConclusionsThe presence of nocturia was associated with erectile dysfunction, systemic vascular events, higher mortality, and indicated poor health in male with type 2 diabetic mellitus.
影响因子：
2.1
作者：
Homma, Yukio;Yoshida, Masaki;Nishizawa, Osamu
通讯作者：
Nishizawa, Osamu
影响因子：
5.8
作者：
Bhasin, Shalender;Cunningham, Glenn R.;Montori, Victor M.
通讯作者：
Montori, Victor M.
影响因子：
--
作者：
Wang, C.;Nieschlag, E.;Wu, F. C. W.
通讯作者：
Wu, F. C. W.