Clinical Correlates of Smoking Status in Men and Women with Opioid Use Disorder.

Clinical Correlates of Smoking Status in Men and Women with Opioid Use Disorder.
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患有阿片类药物使用障碍的男性和女性吸烟状况的临床相关性。

DOI:
10.1080/10826084.2020.1725056
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发表时间:
2020
影响因子:
2
通讯作者:
Weiss,RogerD
Weiss,RogerD
中科院分区:
医学4区
文献类型:
--
作者:
McHugh,RKathryn;Janes,AmyC;Griffin,MargaretL;Taghian,Nadine;Greenfield,ShellyF;Weiss,RogerD

文献摘要

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背景:吸烟在阿片类药物使用障碍 (OUD) 人群中非常普遍,并且是该人群发病率和死亡率的一个重要因素。然而,人们对吸烟和不吸烟的 OUD 患者之间的差异知之甚少。 目的:我们的目的是调查寻求治疗的 OUD 成人吸烟和不吸烟之间的差异。方法:参与者(N= 568;30% 女性)完成了一系列自我报告问卷,包括当前吸烟状况和每天吸烟数量的测量以及临床特征(例如渴望、焦虑)的测量。结果:在总样本中,77% 是当前吸烟者。多变量逻辑回归确定海洛因使用(OR = 2.20,95% CI = 1.38,3.53)和年轻(OR = 0.97,95% CI = 0.95,0.997)与吸烟状况有很强的相关性;其他特征不显着。年龄较大和对阿片类药物的渴望与每天吸更多的香烟有关。值得注意的是,这些模式对于男性和女性来说是不同的。男性对阿片类药物的渴望(B= 0.62,SEB= 0.24)与男性吸烟的数量有关,而女性焦虑(B= 0.39,SEB= 0.19)与吸烟的数量有关。结论:过去一个月使用海洛因的 OUD 成年人更有可能是当前吸烟者。吸烟可能性没有观察到性别差异;然而,男性和女性吸烟状况和严重程度的预测因素不同。
Background: Smoking is highly prevalent in people with opioid use disorder (OUD) and is a significant contributor to morbidity and mortality in this population. However, little is known about the differences between those with OUD who do and do not smoke cigarettes.Objectives: Our aim was to investigate differences between treatment-seeking adults with OUD who did and did not smoke. Methods: Participants (N= 568; 30% female) completed a battery of self-report questionnaires including measures of current smoking status and number of cigarettes smoked per day as well as measures of clinical characteristics (e.g. craving, anxiety).Results: Of the total sample, 77% were current smokers. Multivariable logistic regression identified heroin use (OR = 2.20, 95% CI = 1.38, 3.53) and younger age (OR = 0.97, 95% CI = 0.95, 0.997) as strong correlates of smoking status; other characteristics were not significant. Older age and opioid craving were associated with more cigarettes smoked per day. Notably, these patterns differed for males and females; opioid craving (B= 0.62, SEB= 0.24) was associated with the number of cigarettes smoked among men, and anxiety (B= 0.39, SEB= 0.19) was associated with the number of cigarettes smoked among women.Conclusion: Adults with OUD who used heroin in the past month were more likely to be current smokers. No sex differences were observed in likelihood of smoking; however, the predictors of smoking status and severity differed between men and women.