Radiation therapy for recurrent esophageal carcinoma

Radiation therapy for recurrent esophageal carcinoma
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复发性食管癌的放射治疗

DOI:
10.11182/jastro1989.8.35
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发表时间:
1996
期刊:
--
影响因子:
--
通讯作者:
M. Abe
M. Abe
中科院分区:
--
文献类型:
--
作者:
N. Sakamoto;Y. Nishimura;M. Mitsumori;M. Hiraoka;K. Ono;M. Abe

文献摘要

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1980 ~ 1994年,京都大学附属医院对36例局部复发食管癌患者进行了放射治疗。分析局部缓解率和生存率。患者2年和5年累积生存率均为13%。在生存率终点的单变量分析中评价治疗前和治疗参数。肿瘤大小(3 cm vs. 3 cm)和初始治疗(手术与RT)是生存率的重要变量。除了这些参数外,初始治疗和复发之间的间隔(6个月vs. 6个月),复发时远处转移,复发部位(纵隔淋巴结,颈部淋巴结与食管,腹部淋巴结)也影响生存率,但不显着。在治疗方法方面,加速超分割治疗的所有三种肿瘤均显示
Abstract Between 1980 and 1994, 36 patients with loco-regional recurrent esophageal cancer were treated with radiation therapy(RT) at Kyoto University Hospital. Local response and survival rates of the patients were analyzed. The 2-and 5-year cumulative survival rates of the patients were both 13%. Pretreatment and treatment parameters were evaluated in an univariate analysis for the endpoint of survival rates. Tumor size (s 3 cm vs.> 3 cm) and initial treatment (surgery vs. RT) were significant variables for survival rates. In addition to the parameters, interval between initial treatment and recurrence(•… 6 months vs.> 6 months), distant metastasis at the time of recurrence, and recurrent sites (mediastinal lymph nodes, neck lymph nodes vs. esophagus, abdominal lymph nodes) also affected the survival rate, although not significantly. In terms of treatment methods, all three tumors treated with accelerated hyperfractionation showed