Development and multi-site validation of a new condition-specific quality of life measure for eating disorders
Development and multi-site validation of a new condition-specific quality of life measure for eating disorders
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DOI：
10.1186/1477-7525-5-23
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发表时间：
2007-04-30
影响因子：
3.6
通讯作者：
Brown, Krista E.
中科院分区：
文献类型：
--
作者：
Adair, Carol E.;Marcoux, Gisele C.;Brown, Krista E.
背景：在饮食失调（EDs）治疗中，结果测量传统上侧重于症状减轻，而不是功能或生活质量（QoL）。一般的生活质量测量对某些诊断缺乏敏感性，许多对饮食失调患者没有反应。本文描述了一种针对青少年和成人饮食失调患者的特定条件生活质量测量方法——饮食失调生活质量量表（EDQLS）的开发和验证。方法：采用多来源、多阶段的方法，在ED患者、家属和ED治疗人员的参与下，制定ED qls。领域和项目开发的来源包括39篇文章，12个病人和10个治疗提供者访谈，以及31个来自互联网的第一人称叙述。四个阶段的验证和预测试涉及17名患者、10名家庭成员和18名提供者，将12个领域的233个项目减少到40个项目。这些项目在41名ED患者中进行了初步测试。结果：最后的仪器在12个站点的171个14 - 60岁的ed患者中进行了验证。所有项目均表现出良好的分散性。总原始平均分为110分（SD 27.6），满分为200分，分数越高，生活质量越好。内部一致性极好（Cronbach's α = 0.96），子量表内部一致性范围为α。36。79为强有力的整体结构和一些多维性提供了证据。根据edi2的严重程度，平均EDQLS的显著差异支持了有效性(F= 95.3, p
Background: In eating disorders (EDs) treatment, outcome measurement has traditionally focused on symptom reduction rather than functioning or quality of life (QoL). Generic QoL measures lack sensitivity for some diagnoses and many not be responsive in eating disorder patients. This article describes the development and validation of a condition-specific QoL measure for adolescents and adults with eating disorders - the Eating Disorders Quality of Life Scale (EDQLS).Methods: Multi-source and multi-stage methods were used to develop the EDQLS, with participation of patients with EDs, their family members and ED treatment providers. Sources for domain and item development included 39 articles, 12 patient and 10 treatment provider interviews, and 31 first person narratives from the internet. Four stages of validation and pre-testing involving 17 patients, 10 family members and 18 providers reduced 233 items to 40 items in 12 domains. These items were pilot tested in 41 ED patients.Results: The final instrument was then validated in a 12 site sample of 171 individuals aged 14 - 60 with EDs. All items showed good dispersion. The total raw mean score was 110 out of 200 (SD 27.6) with higher scores indicating better QoL. Internal consistency was excellent (Cronbach's alpha =.96) and subscale internal consistency ranged from alpha .36 to.79 providing evidence for a strong overall construct and some multi-dimensionality. Validity was supported by significant differences in mean EDQLS according to severity levels on the EDI-2 (F= 95.3, p