Effect of caffeine and ephedrine ingestion on anaerobic exercise performance
Effect of caffeine and ephedrine ingestion on anaerobic exercise performance
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DOI：
10.1097/00005768-200108000-00024
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发表时间：
2001-08-01
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影响因子：
--
通讯作者：
Ellerington, K
中科院分区：
文献类型：
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作者：
Bell, DG;Jacobs, I;Ellerington, K
目的：在高强度有氧运动中，摄入咖啡因（C）和麻黄碱（E）的混合物可以缩短疲劳时间。C和E的CNS刺激被认为是改善的机制的一部分。人们认为这种唤醒在无氧运动中也可能是有益的。本研究旨在探讨C、E. C + E摄入对无氧运动成绩的影响。方法：采用两组动物，分别观察C和E对无氧运动能力的影响。组I（WIN）由16名健康的未经训练的男性受试者组成，他们进行了30-s Wingate试验。第2组（MAOD组）为8名未经训练的健康男性受试者，进行超负荷（125%（V）/dot O-2 peak）循环运动至力竭，测定最大累积氧亏。试验开始后1.5天摄入C（5 mg.kg（-1）），E（1 mg. kg（-1）），C+E的组合，或安慰剂（P）。所有试验均为随机双盲试验。在运动前服用药物后，以及运动后3、5和10分钟再次测定血液样品的乳酸盐和葡萄糖。在运动前和运动后10分钟的血液样本中测量了儿茶酚胺。结果如下：麻黄碱增加Wingate试验早期的功率输出，而C增加MAOD试验中的力竭时间和O-2缺乏，C。E和C + E增加血乳酸、葡萄糖和儿茶酚胺水平。结论：无氧运动能力的提高可能是E刺激中枢神经系统和C刺激骨骼肌的结果。
Purpose: Ingestion of a combination of caffeine (C) and ephedrine (E) prolongs time to exhaustion during high-intensity aerobic exercise. CNS stimulation by C and E was proposed as part of the mechanism for the improvement. It was thought that this arousal might also be of benefit during anaerobic exercise. The purpose of this study was to investigate the effect of C, E. and C + E ingestion on performance of anaerobic exercise. Methods: Two groups were used to evaluate the effect of C and E on anaerobic performance. Group I (WIN) consisted of 16 healthy untrained male subjects who performed a 30-s Wingate test. Group 2 (MAOD) consisted of 8 healthy untrained male subjects who performed a supramaximal (125%(V) over dot O-2peak) cycle exercise trial to exhaustion to determine maximum accumulated oxygen deficit. The trials commenced 1.5 It after ingesting either C (5 mg.kg(-1)), E (1 mg.kg(-1)), a combination of C+E, or a placebo (P). All trials were randomized and double blind. Blood samples were assayed for lactate and glucose post drug ingestion just before exercise, and again 3, 5, and 10 min post exercise. Catecholamines were measured in the preexercise and 10-min postexercise blood samples. Results: Ephedrine increased power output during the early phase of the Wingate test, whereas C increased time to exhaustion and O-2 deficit during the MAOD test, C. E, and C + E increased blood lactate, glucose, and catecholamine levels. Conclusion: The improvement in anaerobic exercise performance is likely a result of both stimulation of the CNS by E and skeletal muscle by C.