Analysis of 1983 cases of malignant lymphoma in Thailand according to the World Health Organization classification

Analysis of 1983 cases of malignant lymphoma in Thailand according to the World Health Organization classification
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DOI:
10.1016/j.humpath.2003.10.007
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发表时间:
2004-02-01
期刊:
影响因子:
3.3
通讯作者:
Sukpanichnant, S
Sukpanichnant, S
中科院分区:
医学3区
文献类型:
--
作者:
Sukpanichnant, S

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研究大量的恶性淋巴瘤是重要的,以增加我们对这种疾病的理解。根据世界卫生组织的分类系统,1983例淋巴瘤病例被归类为非霍奇金淋巴瘤(NHL)(92.1%)或霍奇金淋巴瘤(HL)(7.9%)。NHL中B细胞型占75%,T细胞型占25%。弥漫性大B细胞淋巴瘤、未指明的外周T细胞淋巴瘤、滤泡性淋巴瘤、结外边缘区B细胞淋巴瘤、前体T淋巴母细胞淋巴瘤和伯基特淋巴瘤占所有NHL病例的84.3%。混合细胞型和结节硬化型占发现的HL病例的77.7%。AD总体上以男性为主,但不同类型淋巴瘤的性别分布有所不同,在老年受试者中观察到女性占优势。B细胞NHL的发病率随年龄的变化具有特征性:在第三个十年为60%,此后增加,在第七个十年后达到90%。滤泡性淋巴瘤在曼谷的高频率,而在东北地区的低频率和HL在南部地区的高频率是显著的(P
Studying a large series of malignant lymphoma is important to increasing our understanding of this disease. Based on the World Health Organization classification system, 1983 cases of lymphoma at Siriraj Hospital were classified as either non-Hodgkin lymphoma (NHL) (92.1%) or Hodgkin lymphoma (HL) (7.9%). The NHL cases were 75% B cell type and 25% T cell type. Diffuse large B-cell lymphoma, unspecified peripheral T-cell lymphoma, follicular lymphoma, extranodal marginal zone B-cell lymphoma, precursor T lymphoblastic lymphoma, and Burkitt lymphoma accounted for 84.3% of all NHL cases found. Mixed cellularity and nodular sclerosis types constituted 77.7% of the HL cases found. AD overall male preponderance was observed, but sex distribution differed among various types of lymphoma, and a female preponderance was observed in the elderly subjects. Changes in the frequency of B-cell NHL by age were characteristic: 60% in the third decade, and increases thereafter, reaching 90% after the seventh decade. High frequency of follicular lymphoma in Bangkok but low frequency in the Northeastern region and high frequency of HL in the Southern region were significant (P