Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task
Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task
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DOI：
10.1017/s1355617708090127
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发表时间：
2009-01-01
影响因子：
2.6
通讯作者：
Burke, Teresa E.
中科院分区：
文献类型：
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作者：
Blanco-Campal, Alberto;Coen, Robert F.;Burke, Teresa E.
本研究比较了两种广泛使用的回溯性记忆测验(Rivermead段落回忆测验和CERAD词表测验)与两种广泛使用的回溯记忆测验(Rivermead段落回忆测验和CERAD词表测验)在检测疑似阿尔茨海默病病因(MCI-AD)(N=19)和正常对照组(N=21)轻度认知损害时的相对区分效能。统计分析表明PM任务对MCI-AD的检测具有较高的区分性。事实证明，非特定-非突出条件在检测MCI-AD时特别有用，这可能反映了任务的难度，需要更多的战略性注意资源来监控PM线索。截止值为
We investigated the relative discriminatory efficacy of an event-based prospective memory (PM) task, in which specificity of the instructions and perceptual salience of the PM cue were manipulated, compared with two widely used retrospective memory (RM) tests (Rivermead Paragraph Recall Test and CERAD-Word List Test), when detecting mild cognitive impairment of suspected Alzheimer's disease etiology (MCI-AD) (N = 19) from normal controls (NC) (N = 21). Statistical analyses showed high discriminatory capacity of the PM task for detecting MCI-AD. The Non-Specific-Non-Salient condition proved particularly useful in detecting MCI-AD, possibly reflecting the difficulty of the task, requiring more strategic attentional resources to monitor for the PM cue. With a cutoff score of