Genome-edited foods
Genome-edited foods
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DOI：
10.1038/s44222-023-00115-8
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发表时间：
2023-10
期刊：
影响因子：
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通讯作者：
Aytug Tuncel;Changtian Pan;T. Sprink;Ralf Wilhelm;R. Barrangou;Li Li-Li;Patrick M. Shih;Rajeev K. Varshney;Leena Tripathi;Joyce Van Eck;K. Mandadi;Yiping Qi
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文献类型：
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作者：
Aytug Tuncel;Changtian Pan;T. Sprink;Ralf Wilhelm;R. Barrangou;Li Li-Li;Patrick M. Shih;Rajeev K. Varshney;Leena Tripathi;Joyce Van Eck;K. Mandadi;Yiping Qi
基因组编辑可以通过提高作物产量和动物生产力来改变农业和塑造粮食的未来，这反过来又可以帮助实现不断增长的世界人口的粮食安全。基于CRISPR-CAS的技术是应用于各种食品的强大的基因编辑工具。在这篇综述中，我们讨论了CRISPR-CAS的应用，旨在通过大量营养素工程和生物强化或减少抗营养素的数量来增加作物的营养价值。我们研究了CRISPR-CAS在改善作物味道和减少收获后损失以提高消费者接受度和减少食物浪费方面的作用。我们还重点介绍了动物性食品和益生菌的基因编辑。我们总结了世界范围内批准转基因食品的法规和逐渐演变的公众观点。最后，我们探索了可以帮助我们提高基因组编辑技术的效率和全球市场对基因组编辑食品的接受度的策略，并将该技术推广到低资源环境。
Genome editing can transform agriculture and shape the future of food by improving crop yields and animal productivity, which in turn can help to achieve food security for the growing world population. CRISPR–Cas-based technologies are powerful gene editing tools that are applied to various food products. In this Review, we discuss the applications of CRISPR–Cas aimed at increasing the nutritional value of crops through macronutrient engineering and biofortification or the reduction of the amount of antinutrients. We examine the role of CRISPR–Cas in improving the flavour of crops and reducing post-harvest losses to increase consumer acceptance and decrease food waste. We also highlight the gene editing of animal food products and probiotics. We summarize the regulations for approval of gene-edited foods worldwide and the progressively evolving public view. Finally, we explore the strategies that can help to enhance the efficiency of genome editing techniques and the acceptance of genome-edited foods in the global market, and extend the technology to low-resource settings.