Preliminary histopathological observation of Q-switched ruby laser radiation on dermal tattoo pigment in man.
Preliminary histopathological observation of Q-switched ruby laser radiation on dermal tattoo pigment in man.
复制标题
Q开关红宝石激光辐射对人体真皮纹身色素的初步组织病理学观察。
DOI：
10.1016/0022-4804(68)90090-5
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发表时间：
1968
期刊：
影响因子：
--
通讯作者：
R. Chase
中科院分区：
文献类型：
--
作者：
D. Laub;R. Yules;M. Arras;D. E. Murray;L. Crowley;R. Chase
方法本研究的患者是有深色纹身的白人，是实验的志愿者。应用Q开关（10至20纳秒脉冲持续时间）红宝石（6943埃）激光，能量密度从2至7.3焦耳/平方厘米变化。光束由长焦距透镜聚焦。受试者被定位在离透镜不同的距离处，提供能量密度的变化。治疗是在没有预谋或任何类型的麻醉的情况下进行的。病人戴着激光太阳镜。以小增量改变激光能量密度，以确定临界或最佳剂量水平。4例患者接受治疗并随访2 ~ 4个月。连续活检，保存在福尔马林中，并用苏木精和伊红染色。
METHODThe patients in this study were Caucasians with dark-colored tattoos and were volunteers for the experiment. Q-switched(lo-to 20-nanosecond pulse duration) ruby (6943 Angstroms) laser was applied with energy density varying from 2 to 7.3 joules per square centimeter. The beam was focused by a long focal length lens. The subject was positioned at varying distances from the lens, providing variation of the energy density. The therapy was done without premeditation or any type of anesthesia. The patients wore laser sunglasses. The laser energy density was changed in small increments in order to determine the critical or optimal dosage level. Four patients were treated and followed for 2 to 4 months. Serial biopsies were taken, preserved in formalin, and stained with hematoxylin and eosin.