BIOCHEMICAL CHARACTERIZATION OF SOME SPECIES OF TRYPANOSOMA (SCHIZOTRYPANUM) FROM BATS (MICROCHIROPTERA)
BIOCHEMICAL CHARACTERIZATION OF SOME SPECIES OF TRYPANOSOMA (SCHIZOTRYPANUM) FROM BATS (MICROCHIROPTERA)
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DOI：
10.4269/ajtmh.1978.27.483
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发表时间：
1978-01-01
影响因子：
3.3
通讯作者：
BARRETT, TV
中科院分区：
文献类型：
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作者：
BAKER, JR;MILES, MA;BARRETT, TV
锥虫属从欧洲和拉丁美洲的蝙蝠（Microchiroptera）中分离出10种蝙蝠的DNA，测定了它们的核DNA和动体DNA的浮力密度以及6种同工酶的电泳图谱。根据这些标准，它们被分成3个不同的组。dionisii和T. vespertilionis）和1个美洲种。T. Dionisii在体外也可通过其形态分离。地理位置和DNA浮力密度表明，美国种群与T. cruzi比欧洲物种，虽然他们从它略有不同，在动塑性DNA密度和非感染小鼠。其他研究人员研究的类似股票已被证明不同于T。cruzi在降低感染性，缺乏自然协会与锥蝽亚科，并在抗原组成。锥虫属Schizotrypanum亚属的锥虫与锥虫属的锥虫不同。克鲁斯公司应作为一个独立的亚种，T.克鲁奇马林克尔莱海峡nov. T.克鲁斯公司成为了T. cruzi cruzi查加斯1909年。
Trypanosoma (Schizotrypanum) spp. isolated from bats (Microchiroptera) in Europe and Latin America were examined by determining the buoyant densities of their nuclear and kinetoplastic DNA and the electrophoretic patterns of 6 isoenzymes. By these criteria they were separated into 3 distinct groups.sbd.2 from Europe (T. dionisii and T. vespertilionis) and 1 from America. T. dionisii was also separable by its morphology in vitro. Geographical location and DNA buoyant densities suggested that the American stocks were more closely related to T. cruzi than to the European species, though they differed from it marginally in kinetoplastic DNA density and in being non-infective to mice. Similar stocks studied by other workers have been shown to differ from T. cruzi in reduced infectivity to, and lack of natural association with Triatominae, and in antigenic composition. Trypanosomes of the subgenus Schizotrypanum occurring naturally in Microchiroptera and differing from T. cruzi s.s. should be treated as a distinct subspecies, T. cruzi marinkellei ssp. nov. T. cruzi s.s. becomes the nominate subspecies T. cruzi cruzi Chagas 1909.