MONDO: a neutron tracker for particle therapy secondary emission characterisation
MONDO: a neutron tracker for particle therapy secondary emission characterisation
复制标题
MONDO：用于粒子治疗二次发射特征描述的中子跟踪器
DOI：
10.1088/1361-6560/aa623a
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发表时间：
2017-04-21
影响因子：
3.5
通讯作者：
Sarti, A.
中科院分区：
文献类型：
--
作者：
Marafini, M.;Gasparini, L.;Sarti, A.
肿瘤控制是在粒子治疗中使用粒子和离子进行的，其高辐照精度提高了治疗的有效性，同时保留了目标体积周围的健康组织。剂量范围监测装置使用光子和带电粒子产生的光束与病人的身体相互作用已经提出，但还没有尝试利用检测丰富的中子成分。由于中子可以在远离肿瘤区域的地方释放大量的剂量，为了改进治疗计划系统（TPS）软件，迫切需要精确测量它们的通量、产生能量和角度分布。因此，不仅可以预测靶区的正常组织毒性，还可以预测全身晚期并发症的风险。上述问题强调了致力于中子产生的精确特征的实验努力的重要性，旨在测量它们的丰度、发射点和产生能量。在MONDO（强子治疗中子剂量监测）项目中，针对高检测效率和高回溯精度的中子探测器所面临的技术挑战进行了解决，其主要目标是开发一种能够靶向快中子和超快中子的跟踪探测器。探测器内部中子所经历的两个连续的弹性散射相互作用的完整重建将用于测量它们的能量和方向。本文介绍了使用FLUKA软件进行MC模拟的初步结果，以及DSiPM（数字SiPM）读出实现。本文还讨论了专为MONDO跟踪器量身定制的新型探测器读出实现，并报告了采用所提出的中子跟踪策略可实现的中子探测效率。
Tumour control is performed in particle therapy using particles and ions, whose high irradiation precision enhances the effectiveness of the treatment, while sparing the healthy tissue surrounding the target volume.Dose range monitoring devices using photons and charged particles produced by the beam interacting with the patient's body have already been proposed, but no attempt has been made yet to exploit the detection of the abundant neutron component.Since neutrons can release a significant dose far away from the tumour region, precise measurements of their flux, production energy and angle distributions are eagerly sought in order to improve the treatment planning system (TPS) software. It will thus be possible to predict not only the normal tissue toxicity in the target region, but also the risk of late complications in the whole body.The aforementioned issues underline the importance of an experimental effort devoted to the precise characterisation of neutron production, aimed at the measurement of their abundance, emission point and production energy.The technical challenges posed by a neutron detector aimed at high detection efficiency and good backtracking precision are addressed within the MONDO (monitor for neutron dose in hadrontherapy) project, whose main goal is to develop a tracking detector that can target fast and ultrafast neutrons.A full reconstruction of two consecutive elastic scattering interactions undergone by the neutrons inside the detector material will be used to measure their energy and direction. The preliminary results of an MC simulation performed using the FLUKA software are presented here, together with the DSiPM (digital SiPM) readout implementation. New detector readout implementations specifically tailored to the MONDO tracker are also discussed, and the neutron detection efficiency attainable with the proposed neutron tracking strategy are reported.