Diabetic maculopathy. A critical review highlighting diffuse macular edema.
Diabetic maculopathy. A critical review highlighting diffuse macular edema.
复制标题
糖尿病黄斑病。
DOI：
10.1016/s0161-6420(83)34388-8
复制
发表时间：
1983
期刊：
影响因子：
13.7
通讯作者：
Bresnick,GH
中科院分区：
文献类型：
--
作者：
Bresnick,GH
视网膜缺血和水肿是糖尿病性黄斑病的两个主要视网膜内成分。局灶性黄斑水肿是由视网膜微动脉瘤和毛细血管段扩张的局灶性渗漏引起的；弥漫性水肿是由整个后极部弥漫性扩张的视网膜毛细血管渗漏引起的。弥漫性黄斑水肿可能会因心脏或肾功能衰竭以及高血压等全身因素而加剧。据推测，视网膜色素上皮屏障和运输功能的功能障碍可能导致弥漫性黄斑水肿的问题。已经提出了治疗弥漫性水肿的激光网格光凝新技术。据推测，紊乱的视网膜色素上皮的光凝清创术可能是该治疗的作用机制。
Retinal ischemia and edema are the two major intraretinal components of diabetic maculopathy. Focal macular edema is caused by focal leakage from retinal microaneurysms and dilated capillary segments; diffuse edema is caused by leakage from diffusely dilated retinal capillaries throughout the posterior pole. Diffuse macular edema may be exacerbated by systemic factors such as cardiac or renal failure, and hypertension. It is postulated that dysfunction of the retinal pigment epithelial barrier and transport functions might contribute to the problem of diffuse macular edema. Newer techniques of laser grid photocoagulation for diffuse edema have been proposed. It is postulated that photocoagulative debridement of a disordered retinal pigment epithelium could be a mechanism of action of this treatment.