Golgi: Interactive Online Brain Mapping
Golgi: Interactive Online Brain Mapping
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DOI：
10.3389/fninf.2015.00026
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发表时间：
2015-11-17
影响因子：
3.5
通讯作者：
Swanson, Larry W.
中科院分区：
文献类型：
--
作者：
Brown, Ramsay A.;Swanson, Larry W.
Golgi (http://www.usegolgi.com) 是大鼠大脑的原型交互式脑图，可帮助研究人员直观地与神经解剖学、连接组学以及细胞和化学结构进行交互。大量的“-omic”数据催生了新的方法来帮助研究人员将离散的发现与神经系统的更大背景联系起来。在这里，我们探讨高尔基体的基本推理和技术，以及我们的设计决策如何平衡构建科学上有用且可用的工具的限制。我们通过研究涉及伏核的丘脑皮质回路的案例研究来展示高尔基体如何增强连接组学文献检索，并探索高尔基体在系统神经科学和连接组学方面的潜力和未来发展方向。
Golgi (http://www.usegolgi.com) is a prototype interactive brain map of the rat brain that helps researchers intuitively interact with neuroanatomy, connectomics, and cellular and chemical architecture. The flood of "-omic" data urges new ways to help researchers connect discrete findings to the larger context of the nervous system. Here we explore Golgi's underlying reasoning and techniques and how our design decisions balance the constraints of building both a scientifically useful and usable tool. We demonstrate how Golgi can enhance connectomic literature searches with a case study investigating a thalamocortical circuit involving the Nucleus Accumbens and we explore Golgi's potential and future directions for growth in systems neuroscience and connectomics.