Longevity of the placebo effect in the therapeutic angiogenesis and laser myocardial revascularization trials in patients with coronary heart disease

Longevity of the placebo effect in the therapeutic angiogenesis and laser myocardial revascularization trials in patients with coronary heart disease
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DOI:
10.1016/j.amjcard.2005.02.013
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发表时间:
2005-06-15
影响因子:
2.8
通讯作者:
Laham, RJ
Laham, RJ
中科院分区:
医学3区
文献类型:
--
作者:
Rana, JS;Mannam, A;Laham, RJ

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安慰剂治疗的长期有益效果在血管生成和激光心肌血运重建试验中进行了评估,这些试验在终末期冠心病患者中进行。平均心绞痛分级、平板运动时间和生活质量的改善在随访30 +/- 6个月时基本维持。效果的持续性不能作为证据或疗效,双盲试验在该患者人群中至关重要。(c)2005年,Excerpta Medica Inc.
The long-term beneficial effects of placebo therapy were evaluated in angiogenesis and laser myocardial revascularization trials in patients who had end-stage coronary heart disease. Improvements in mean angina class, exercise treadmill time, and quality of life were mostly maintained at 30 +/- 6 months of follow-up. Persistence of effect cannot be used as evidence or efficacy, and double-blinded trials are essential in this patient population. (c) 2005 by Excerpta Medica Inc.