Acupuncture Treatment for Dyspnea due to Combined Pulmonary Fibrosis and Emphysema: A Case Report.
Acupuncture Treatment for Dyspnea due to Combined Pulmonary Fibrosis and Emphysema: A Case Report.
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针灸治疗合并肺纤维化和肺气肿引起的呼吸困难：一例报告。
DOI：
10.1089/acm.2015.0132
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Minatoguchi S.
中科院分区：
文献类型：
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作者：
Matsumoto-Miyazaki J;Miyazaki N;Nishiwaki A;Endo J;Ushikoshi H;Ohno Y;Minatoguchi S.
目的：特发性肺纤维化合并肺气肿（CPFE）是一种以肺上叶气肿和肺下叶纤维化为特征的综合征。运动性呼吸困难（DOE）是CPFE的主要症状。我们报告一个病人DOE由于CPFE谁是成功治疗acupuncture.Design：Case report.Case presentation：一个72岁的日本男子与4年的DOE的历史被诊断为CPFE 2年前在另一家医院。他接受了标准的西医治疗，其中包括支气管扩张剂。然而，他的情况并没有改善。结果：针刺治疗10周后，6 min步行试验结果（6 min步行距离379 m，最低血氧饱和度86%，改良博格呼吸困难量表评分2个单位）均优于基线（352 m，84%，4个单位）。这些值在30周（470个月，88%，1个单位）和60周（473个月，85%，2个单位）时均保持不变。血清间质生物标志物，Krebs冯登伦根和表面活性蛋白-D，开始针灸therapy.Conclusion后下降：CPFE患者表现出改善呼吸困难评分，运动耐量，血清生物标志物在1年的针灸治疗过程中。针刺治疗可作为缓解慢性肺纤维化所致DOE的有效辅助治疗。应该进行一项大型的、设计良好的队列研究，包括接受针灸治疗的CPFE患者。
Objective:Combined idiopathic pulmonary fibrosis with pulmonary emphysema (CPFE) is a syndrome with a characteristic presentation of upper lobe emphysema and lower lobe fibrosis. Dyspnea on exertion (DOE) is a major symptom of CPFE. We report a patient with DOE due to CPFE who was successfully treated with acupuncture.Design:Case report.Case presentation:A 72-year-old Japanese man with a 4-year history of DOE was diagnosed with CPFE 2 years previously in another hospital. He received standard Western medicine treatment, which included bronchodilators. However, his DOE did not improve. Consequently, he visited our hospital for acupuncture treatment and received acupuncture treatment once a week for 1 year.Results:After 10 weeks of acupuncture treatment, the results of the 6-minute walk test (6-minute walking distance, 379 m; lowest oxygen saturation, 86%; modified Borg dyspnea scale score: 2 units) were better than those at baseline (352 m, 84%, 4 units, respectively). These values were sustained at both 30 weeks (470 m, 88%, 1 unit) and 60 weeks (473 m, 85%, 2 units). Serum interstitial biomarkers, Krebs von den Lungen and surfactant protein-D, decreased after commencement of acupuncture therapy.Conclusion:A patient with CPFE showed improvements in dyspnea scores, exercise tolerance, and serum biomarkers during a 1-year course of acupuncture treatment. Use of acupuncture might be an effective adjunct therapy in relieving DOE due to CPFE. A large, well-designed cohort study that includes patients with CPFE treated with acupuncture should be conducted.