Childhood abuse or neglect is associated with increased vasomotor symptom reporting among midlife women
Childhood abuse or neglect is associated with increased vasomotor symptom reporting among midlife women
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DOI：
10.1097/gme.0b013e31805fea75
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发表时间：
2008-01-01
影响因子：
2.7
通讯作者：
Matthews, Karen A.
中科院分区：
文献类型：
--
作者：
Thurston, Rebecca C.;Bromberger, Joyce;Matthews, Karen A.
目的：本研究检验了这样的假设，即童年时期遭受虐待或忽视的女性在更年期过渡期间出现潮热和盗汗的可能性会增加。设计：这项假设在参与全国女性健康心理健康研究的 332 名白人和非裔美国女性中进行了评估，该研究是一项针对更年期女性的前瞻性调查。使用儿童创伤问卷对童年虐待和忽视进行了一次测量。 8 年来，每年都会报告血管舒缩症状（有/无潮热、盗汗）。使用广义估计方程估计虐待和血管舒缩症状之间的关联。结果：在年龄调整模型中，童年虐待或忽视与潮热（比值比 = 1.73，95% CI：1.23-2.43）和盗汗（比值比 = 1.75，95% CI：1.26-2.43）报告增加相关。结果在多变量模型以及多种类型的虐待和忽视中持续存在。结论：儿童期虐待和忽视的经历与成年后血管舒缩症状报告的增加有关。童年时期虐待和忽视的后遗症可能会持续到成年，影响中年血管舒缩症状的发生。
Objectives: This study tested the hypothesis that women exposed to childhood abuse or neglect would have an increased likelihood of reporting hot flashes and night sweats during the menopausal transition.Design: This hypothesis was evaluated in 332 white and African American women participating in the Study of Women's Health Across the Nation Mental Health Study, a prospective investigation of women transitioning through menopause. Childhood abuse and neglect were measured once with the Child Trauma Questionnaire. Vasomotor symptoms (any/none hot flashes, night sweats) were reported annually over 8 years. Associations between maltreatment and vasomotor symptoms were estimated with generalized estimating equations.Results: Childhood abuse or neglect was associated with increased reporting of hot flashes (odds ratio = 1.73, 95% CI: 1.23-2.43) and night sweats (odds ratio = 1.75, 95% CI: 1.26-2.43) in age-adjusted models. Results persisted in multivariable models and across several types of abuse and neglect.Conclusions: The experience of childhood abuse and neglect is associated with increased vasomotor symptom reporting in adulthood. The sequelae of childhood abuse and neglect may persist well into adulthood to influence the occurrence of vasomotor symptoms at midlife.