Accelerated bone formation around titanium dental implants withamorphous calcium phosphate coating in rabbit, in Interface Oral Health Science 2011
Accelerated bone formation around titanium dental implants withamorphous calcium phosphate coating in rabbit, in Interface Oral Health Science 2011
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使用无定形磷酸钙涂层加速兔子钛牙种植体周围的骨形成，发表于 Interface Oral Health Science 2011
DOI：
10.1007/978-4-431-54070-0_69
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
T. Narushima and H. Kawamura
中科院分区：
文献类型：
--
作者：
S. Yokota;J. Kurihara;N. Nishiwaki;S.Tamate;K. Ueda;T. Narushima and H. Kawamura
本研究的目的是研究采用射频磁控溅射技术制造的带有非晶磷酸钙 (ACP) 涂层的钛牙种植体在兔体内的骨反应。采用射频磁控溅射的磷酸钙涂层可以获得高结合强度和薄膜的纳米均匀性。此外，据报道ACP在体外被迅速吸收。将 ACP 涂层和未涂层的植入物放入兔子体内。植入1、2和4周后，通过共振频率分析（RFA）评估植入物稳定性，并通过组织形态学评估骨形成。 ACP 涂层种植体在 RFA 中表现出更高的稳定性，并在 4 周内改善了骨种植体接触比。与未涂层种植体相比，使用射频磁控溅射技术制造的涂有 ACP 的钛牙种植体加速了骨形成。
The aim of this study was to investigate the bone response of titanium dental implant with amorphous calcium phosphate (ACP) coating film fabricated using RF magnetron sputtering in rabbit. Calcium phosphate coating using RF magnetron sputtering acquires high bonding strength and nano-uniformity of films. Moreover, it is reported that ACP was resorbed rapidly in vitro. The ACP-coated and non-coated implants were placed into rabbits. After 1, 2 and 4 weeks of implantation, the implant stability was evaluated by resonance frequency analysis (RFA) and bone formation was also evaluated histomorphometrically. The ACP-coated implants showed higher stability in RFA and improved bone-implant contact ratio in 4 weeks. Titanium dental implant coated with ACP fabricated using RF magnetron sputtering accelerated bone formation compared with that of non-coated implants.