Race/ethnicity and sex differences in progression from drinking initiation to the development of alcohol dependence
Race/ethnicity and sex differences in progression from drinking initiation to the development of alcohol dependence
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DOI：
10.1016/j.drugalcdep.2011.04.024
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发表时间：
2011-11-01
影响因子：
4.2
通讯作者：
Crum, Rosa M.
中科院分区：
文献类型：
--
作者：
Alvanzo, Anika A. H.;Storr, Carla L.;Crum, Rosa M.
背景：先前关于酒精使用障碍过程的研究报道了女性从饮酒开始到酒精依赖的“伸缩”效应比男性更快。然而，很少有基于人群的分析，比较种族/民族亚组来研究酒精依赖的进展，而且对于女性的伸缩效应是否因种族/民族而异也知之甚少。我们研究了在一般人群中比较种族/民族亚组和按种族分层的男性和女性是否存在伸缩效应。方法：本研究使用来自全国酒精及相关疾病流行病学调查（NESARC）第一波的数据，比较了18-44岁的白人、黑人和西班牙裔成年人的全国代表性样本（n=21,106）。事件时间分析比较了三个种族/族裔群体以及每个种族/族裔群体中男性和女性的酒精起始、酒精依赖的开始和从最初使用到酒精依赖的转变的风险。结果：白人在开始饮酒时比黑人和西班牙裔年轻，并且发展为酒精依赖的速度比黑人和西班牙裔快。此外，我们没有发现任何证据表明在任何种族/民族的女性中存在伸缩效应。结论：目前的研究说明了从酒精开始到发展为依赖的转变过程中，种族/民族而非性别的差异。我们的研究结果强调需要进一步研究导致种族/民族差异的因素，以便为文化相关的预防和干预举措提供信息。2011爱思唯尔爱尔兰有限公司版权所有。
Background: Prior studies on the course of alcohol use disorders have reported a "telescoping" effect with women progressing from drinking initiation to alcohol dependence faster than men. However, there is a paucity of population-based analyses that have examined progression to alcohol dependence comparing race/ethnicity subgroups, and little is known about whether the telescoping effect for women varies by race/ethnicity. We examined whether a telescoping effect is present in the general population comparing race/ethnicity subgroups and comparing men and women stratified by race.Methods: This study uses data from Wave I of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) to compare a nationally representative sample of White, Black and Hispanic adults 18-44 years of age (n=21,106). Time to event analyses compare the risk of alcohol initiation, onset of alcohol dependence, and the transition from initial use to onset of alcohol dependence in the three race/ethnicity groups and for males and females in each race/ethnicity group.Results: Whites were younger than Blacks and Hispanics of the same sex at drinking onset and progressed to alcohol dependence at a faster rate than both Blacks and Hispanics. In addition, we found no evidence of a telescoping effect in women for any race/ethnicity group.Conclusions: The present study illustrates differences in the course of transition from alcohol initiation to the development of dependence by race/ethnicity but not sex. Our findings highlight the need for additional study of factors resulting in race/ethnicity differences in order to inform culturally relevant prevention and intervention initiatives. (C) 2011 Elsevier Ireland Ltd. All rights reserved.