Benefit of angiographic spontaneous reperfusion in STEMI: does it extend to diabetic patients?
Benefit of angiographic spontaneous reperfusion in STEMI: does it extend to diabetic patients?
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DOI：
10.1136/hrt.2008.160390
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发表时间：
2009-08-15
期刊：
影响因子：
5.7
通讯作者：
Armstrong, P. W.
中科院分区：
文献类型：
--
作者：
Bainey, K. R.;Fu, Y.;Armstrong, P. W.
背景资料：ST段抬高型心肌梗死（STEMI）的自发再灌注（SR）可改善临床结局，但其在糖尿病患者中的发病率和影响尚不清楚。目的：对STEMI患者的大规模直接经皮冠状动脉介入治疗（PCI）治疗人群的糖尿病队列进行SR的系统分析。方法和结果：对APEX AMI研究中接受直接PCI的4944例患者（15.5%糖尿病患者）进行了评价。11.5%的患者发生SR（定义为PCI前心肌梗死溶栓（TIMI）3级血流）;非糖尿病患者（11.9%）比糖尿病患者（9.2%）更常见（p = 0.028）。SR患者与无SR患者相比，PCI后TIMI 3级血流改善：非糖尿病患者（99.8% vs 90.3%，p
Background: Spontaneous reperfusion (SR) in ST elevation myocardial infarction (STEMI) improves clinical outcome, yet its incidence and impact among diabetic patients is unclear.Objective: To carry out a systematic analysis of SR in the diabetic cohort of a large primary percutaneous coronary intervention (PCI)-treated population with STEMI.Methods and results: 4944 patients (15.5% diabetic) undergoing primary PCI in the APEX AMI study were evaluated. SR defined as pre-PCI Thrombolysis in Myocardial Infarction (TIMI) 3 flow occurred in 11.5% of patients; it was more common in non-diabetic (11.9%) than in diabetic patients (9.2%) (p = 0.028). Patients with SR versus no SR had improved post-PCI TIMI 3 flow: in non-diabetic patients (99.8% vs 90.3%, p