MAINTENANCE OF ION CONCENTRATION GRADIENTS IN THE COLD IN AORTA FROM RAT AND GROUND-SQUIRREL
MAINTENANCE OF ION CONCENTRATION GRADIENTS IN THE COLD IN AORTA FROM RAT AND GROUND-SQUIRREL
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DOI：
10.1152/ajpcell.1979.237.1.c17
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发表时间：
1979-01-01
影响因子：
--
通讯作者：
SOUTH, FE
中科院分区：
文献类型：
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作者：
KAMM, KE;ZATZMAN, ML;SOUTH, FE
大鼠主动脉平滑肌细胞水分和离子含量测定[j]。[参考答案]C。在低温含氧克雷布斯溶液中孵育48小时。冬眠动物地鼠的细胞在7℃的孵育过程中Na和K含量保持在正常水平附近。C.与此形成鲜明对比的是，大鼠的细胞在14和11小时内分别损失了一半的K和获得了一半的Na。大鼠细胞水K浓度[K]降低138 mM，细胞水[Na]升高约148 mM，冬眠细胞K减少10 mM， Na增加13 mM。大鼠和松鼠血管平滑肌能维持17℃的钾含量。C.两种动物血管中二价阳离子Ca和Mg的组织含量均未发生变化。冬眠动物的主动脉平滑肌细胞显然已经适应了这样一种方式，即在长时间暴露于低温下保持离子梯度。
Cell water and ionic content were measured in aortic smooth muscle from rats [R. norvegicus] and ground squirrels [C. tridecemlineatus] during 48 h of incubation in oxygenated Krebs solution held at low temperatures. Cells from the ground squirrel, a hibernator, maintained Na and K contents near normal levels during incubation at 7.degree. C. In sharp contrast, cells from the rat lost K and gained Na with half times of 14 and 11 h, respectively. The K concentration [K] in cell water for the rat decreased 138 mM while [Na] in cell water increased about 148 mM. Cells from the hibernator tended to lose 10 mM K and gain 13 mM Na. Vascular smooth muscle of the rat and squirrel was able to maintain K content at 17.degree. C. Tissue content of the divalent cations Ca and Mg did not change in vessels from either animal. Aortic smooth muscle cells from a hibernator apparently have adapted in such a way as to maintain ionic gradients upon prolonged exposure to low temperatures.