Heavy mutagenesis by tobacco leads to lung adenocarcinoma tumors with KRAS G12 mutations other than G12D, leading KRAS G12D tumors-on average-to exhibit a lower mutation burden.
Heavy mutagenesis by tobacco leads to lung adenocarcinoma tumors with KRAS G12 mutations other than G12D, leading KRAS G12D tumors-on average-to exhibit a lower mutation burden.
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烟草的严重诱变导致肺腺癌肿瘤具有除 G12D 之外的 KRAS G12 突变,导致 KRAS G12D 肿瘤平均表现出较低的突变负担。
DOI:
10.1016/j.lungcan.2021.10.008
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发表时间:
2022
期刊:
影响因子:
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通讯作者:
Townsend,JeffreyP
中科院分区:
文献类型:
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作者:
Tan,Chichun;Mandell,JeffreyD;Dasari,Krishna;Cannataro,VincentL;Alfaro-Murillo,JorgeA;Townsend,JeffreyP