Delineation of the nerve fiber bundles of the infant brain associated with aging using phase difference-enhanced imaging: a preliminary study
Delineation of the nerve fiber bundles of the infant brain associated with aging using phase difference-enhanced imaging: a preliminary study
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使用相位差增强成像描绘与衰老相关的婴儿大脑神经纤维束：初步研究
DOI：
10.1007/s11604-020-00955-z
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发表时间：
2020
影响因子：
2.1
通讯作者：
Hideharu Sugimoto
中科院分区：
文献类型：
--
作者：
Hiroyuki Fujii;Noriko Sato;Yukio Kimura;Atsuhiko Sugiyama;Yoko Shigemoto;Fumio Suzuki;Hiroshi Matsuda;Masayuki Sasaki;Hideharu Sugimoto
本研究的目的是评估脑干神经纤维束的描绘和视放射在T1WI，T2WI和相位差增强（PADRE）图像上与增龄相关的婴儿。材料和方法我们回顾性分析了21例连续的受试者，他们接受了2岁以下的脑MRI检查，没有异常成像结果。两名神经放射科医生使用3分制评价脑干中的8个神经纤维束和视神经辐射，重点是与周围脑实质的对比度。结果1月龄时T2 WI对神经纤维束的显示优于T1 WI，随年龄增长，图像逐渐模糊。在PADRE上，1月龄时几乎所有的神经纤维束都不清晰或不可见，但随着年龄的增长逐渐清晰。年龄与视放射与周围白色物质的信号比呈显著负相关。结论PADRE成像能够显示婴幼儿神经纤维束，随着年龄的增长，其显示逐渐清晰。PADRE、T1WI、T2WI联合应用对婴幼儿神经纤维束的评价有一定价值。
PurposeThe purpose of this study was to evaluate the delineation of nerve fiber bundles in the brainstem and optic radiation in infants associated with aging on T1WI, T2WI, and phase difference-enhanced (PADRE) images.Materials and methodsWe retrospectively reviewed 21 consecutive subjects < 2 years old who underwent brain MRI without abnormal imaging findings. Two neuroradiologists evaluated the eight nerve fiber bundles in the brainstem and optic radiation using a 3-point scale focused on the contrast to surrounding brain parenchyma. We also evaluated the signal ratio of the optic radiation to surrounding white matter on PADRE for each month age.ResultsT2WI was able to delineate nerve fiber bundles better than T1WI at 1 month old, and the images gradually became unclear with aging. On PADRE, almost all nerve fiber bundles were unclear or invisible at 1 month old but gradually became clearer with aging. There was a significant negative correlation between age and the signal ratio of the optic radiation to surrounding white matter.ConclusionsThe PADRE imaging was able to delineate the nerve fiber bundles in infants, and the delineation gradually became clearer with aging. The combination of PADRE, T1WI, and T2WI would be useful for evaluation of nerve fiber bundles in infants.