Figure-ground modulation in awake primate thalamus.
Figure-ground modulation in awake primate thalamus.
复制标题
清醒灵长类动物丘脑的图形-地面调制。
DOI：
10.1073/pnas.1405162112
复制
发表时间：
2015
影响因子：
11.1
通讯作者：
Jones HE
中科院分区：
文献类型：
--
作者：
Jones HE
图形-背景辨别指的是对一个物体（图形）在一个难以描述的背景下的感知。图形-背景检测的神经机制与高级中心和初级视觉皮层之间的反馈相互作用有关，并被认为是全局分析对局部特征编码的影响的指标。在这里，在记录从视觉丘脑的警觉灵长类动物，我们展示了一个强大的增强神经元放电时，图，而不是地面，组件的运动定义的图形-地面刺激位于感受野。在这个范例中，视觉刺激的感受野及其附近的环境是相同的两种条件下，这表明反应增强反映了更高的整合机制。由此看来，产生图形的高阶感知的皮层活动同时又重新进入解剖学上可能的最低水平（丘脑），因此图形的进化表征的签名在一个迭代过程中被印在驱动它的输入上。
Figure-ground discrimination refers to the perception of an object, the figure, against a nondescript background. Neural mechanisms of figure-ground detection have been associated with feedback interactions between higher centers and primary visual cortex and have been held to index the effect of global analysis on local feature encoding. Here, in recordings from visual thalamus of alert primates, we demonstrate a robust enhancement of neuronal firing when the figure, as opposed to the ground, component of a motion-defined figure-ground stimulus is located over the receptive field. In this paradigm, visual stimulation of the receptive field and its near environs is identical across both conditions, suggesting the response enhancement reflects higher integrative mechanisms. It thus appears that cortical activity generating the higher-order percept of the figure is simultaneously reentered into the lowest level that is anatomically possible (the thalamus), so that the signature of the evolving representation of the figure is imprinted on the input driving it in an iterative process.