Predictors of compliance with community-directed ivermectin treatment in Uganda: quantitative results
Predictors of compliance with community-directed ivermectin treatment in Uganda: quantitative results
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DOI：
10.1111/j.1365-3156.2005.01436.x
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发表时间：
2005-07-01
影响因子：
3.3
通讯作者：
Ndyomugyenyi, R
中科院分区：
文献类型：
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作者：
Nuwaha, F;Okware, J;Ndyomugyenyi, R
为了确定影响大规模伊维菌素治疗控制盘尾丝虫病依从性的因素，在乌干达布森伊区进行了一项横断面研究。通过采访从盘尾丝虫病流行的30个聚集区随机选择的839人收集数据。收集了以下方面的信息：遵守伊维菌素治疗的情况、社会人口特征、个人对盘尾丝虫病易感性的认识、对盘尾丝虫病病因/传播的了解、对盘尾丝虫病体征和症状的了解、盘尾丝虫病的治疗、服用伊维丝虫病的益处和危险、伊维丝虫病分发的组织、工作和选择社区药物分销商（ccd）。服用伊维菌素的社会影响和支持，以及遵守伊维菌素治疗的障碍和支持。支持遵医嘱的主要因素是：认为cdd做得很好，认为测量身高是确定伊维菌素剂量的最佳方法，拥有来自家庭的社会支持，认为伊维菌素治疗不需要任何费用，认识到个人患盘尾丝虫病的风险，相信伊维菌素可以预防盘尾丝虫病，并认为无线电支持伊维菌素治疗。伊维菌素治疗依从性的最强预测因子是认为cdd工作良好，校正优势比为5.54 （95% CI: 3.19-9.62）。为了提高对伊维菌素治疗的依从性，需要很好地促进cdd，并应免费分发伊维菌素。有必要进行健康教育，使人们认识到自己有患盘尾丝虫病的危险，并了解使用身高来确定剂量的理由。健康教育应以家庭为对象，使用无线电。
In order to identify the factors influencing compliance with mass ivermectin treatment for onchocerciasis control, a cross-sectional study was carried out in Bushenyi District, Uganda. Data were collected by interviewing 839 individuals who were randomly selected from 30 clusters where onchocerciasis is endemic. Information was collected on compliance with ivermectin treatment, socio-demographic characteristics, perception of personal susceptibility to onchocerciasis, knowledge about cause/transmission of onchocerciasis, knowledge of signs and symptoms of onchocerciasis, treatment of onchocerciasis, benefits and dangers of taking ivermectin, organization of distribution of ivermectin, work and selections of community drug distributors (CDDs), social influence and support to take ivermectin and on barriers and supports towards compliance with ivermectin treatment. The major factors favouring compliance were: perceiving CDDs as doing their work well, believing that measuring height is the best way to determine one's dose of ivermectin, having social support from one's family, saying that ivermectin treatment costs nothing, perceiving personal risk of onchocerciasis, believing that ivermectin prevents onchocerciasis and perceiving radios as supporting treatment with ivermectin. The strongest predictor of compliance with ivermectin treatment is perceiving CDDs as doing their work well with adjusted odds ratios of 5.54 (95% CI: 3.19-9.62). In order to improve compliance with ivermectin treatment, CDDs need to be well-facilitated and ivermectin distribution should be free. Health education is necessary so that people perceive themselves to be at risk of onchocerciasis and to understand the rationale of using height for dose determination. The health education should target the family and use radios.