Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein
Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein
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DOI：
10.1039/b610461d
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发表时间：
2006-01-01
影响因子：
4.9
通讯作者：
Maywald, Matthias
中科院分区：
文献类型：
--
作者：
Reetz, Manfred T.;Peyralans, Jerome J. -P.;Maywald, Matthias
利用定向进化方法来调节锚定于蛋白质的合成非手性金属配体中心的对映选择性的概念已首次在实验上得到实现。
The concept of utilizing the methods of directed evolution for tuning the enantioselectivity of synthetic achiral metal - ligand centers anchored to proteins has been implemented experimentally for the first time.