Embryonic development of the rat cerebellum. I. Delineation of the cerebellar primordium and early cell movements
Embryonic development of the rat cerebellum. I. Delineation of the cerebellar primordium and early cell movements
复制标题
大鼠小脑的胚胎发育。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
S. A. Bayer
中科院分区：
文献类型：
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作者：
J. Altman;S. A. Bayer
使用正常和X射线照射大鼠胚胎的短生存期和长生存期胸苷x线片以及甲基丙烯酸酯包埋组织来描绘小脑的神经上皮来源并追踪最早的细胞运动。小脑基底呈新月形，由两个心室标志区分，即第四脑室脉管端前延伸和胚胎小脑裂。小脑端脉络膜从髓质第四脑室后内侧延伸至脑桥第四脑室外侧隐窝。胚胎小脑裂从尾部开始，在融合的小脑后原基下形成一个单一的中线切口，然后沿着未融合的小脑半部分分裂，首先从峡部分离，然后从桥状脑桥分离。
Short‐survival and long‐survival thymidine radiograms, and methacrylate‐embedded tissue from normal and X‐irradiated rat embryos were used to delineate the neuroepithelial source of the cerebellum and trace the earliest cell movements. The cerebellar anlage, crescent shaped, is demarcated by two ventricular landmarks, the anterior extension of the tela choroidea of the fourth ventricle and the embryonic cerebellar fissure. The cerebellar tela choroidea extends from the medullary fourth ventricle posteromedially to the lateral recess of the pontine fourth ventricle anterolaterally. The embryonic cerebellar fissure begins caudally as a single midline incision beneath the fused posterior cerebellar primordium, then splits to follow the unfused cerebellar halves, first separating each from the isthmus then from the pons.