Minocycline Protects Against the Degeneration of Retinal Neurons in Mice

Minocycline Protects Against the Degeneration of Retinal Neurons in Mice
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米诺环素可防止小鼠视网膜神经元变性

DOI:
10.14218/jerp.2020.00015
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发表时间:
2020
期刊:
影响因子:
--
通讯作者:
Rui Guo
Rui Guo
中科院分区:
--
文献类型:
--
作者:
Rui Guo

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小胶质细胞激活可导致视网膜神经节细胞(RGC)变性。本研究旨在探讨米诺环素对雄性成年C57 BL/6小鼠左眼单侧视神经挤压(ONC)后双侧视网膜中小胶质细胞激活相关的RGCs变性的潜在治疗作用。
Microglia activation can cause degeneration of retinal ganglion cells (RGCs). This study aimed to investigate the potential therapeutic effect of minocycline on microglia activation-related degeneration of RGCs in both retinas after unilateral optic nerve crush (ONC) in the left eye of male adult C57BL/6 mice.