PROPERTIES OF LEARNING AND MEMORY IN DROSOPHILA-MELANOGASTER
PROPERTIES OF LEARNING AND MEMORY IN DROSOPHILA-MELANOGASTER
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DOI：
10.1007/bf00656809
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发表时间：
1977-01-01
期刊：
影响因子：
--
通讯作者：
DUDAI, Y
中科院分区：
文献类型：
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作者：
DUDAI, Y
D.黑腹动物可以在其存在下受到电击后被调节以选择性地避开气味剂（Quinn et.例如，1974年）。报道了果蝇的学习和记忆特性。条件反射行为的主要部分是在一次训练试验后获得的。通过以各种组合使用各种气味剂，可以获得类似的学习程度。苍蝇可以学会一次有选择地避开几种气味，区分同一种气味的不同浓度，并区分气味的混合物。如果不熄灭，选择性回避衰减缓慢，可以检测到数小时，其大小取决于训练的强度。在训练后的前20分钟内，麻醉会破坏记忆，但在训练后不会。野生型菌株和各种形态和行为突变体的学习特性的研究揭示了性能的差异。这些差异不能肯定地归因于学习和记忆本身的差异，因为突变体在行为的其他方面不同，例如，自发活动和趋光性。在测试的野生型菌株中，Canton-S表现最好。
D. melanogaster can be conditioned to avoid an odorant selectively after being shocked in its presence (Quinn et. al., 1974). Learning and memory properties of the flies are reported. The major part of the conditioned behavior is acquired after a single training trial. Similar degrees of learning are obtained by using various odorants in various combinations. The flies can learn to avoid selectively several odorants at a time, to discriminate between different concentrations of the same odorant and to distinguish a mixture of odorants from its components. If not extinguished the selective avoidance decays slowly and can be detected for hours, its magnitude depending upon the intensity of training. Memory can be disrupted by narcosis during approximately the first 20 min after training, but not after. A study of learning properties of wild-type strains and various morphological and behaviorial mutants reveals differences in performance. The differences cannot be attributed with certainty to differences in learning and memory per se, because the mutants differ in other aspects of behavior, e.g., locomotor activity and phototaxis. Of the wild-type strains tested, Canton-S performed the best.