Human cataracta complicata. Clinicopathologic correlation.
Human cataracta complicata. Clinicopathologic correlation.
复制标题
人类复杂性白内障。
DOI：
10.1016/s0161-6420(81)35059-3
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发表时间：
1981
期刊：
影响因子：
13.7
通讯作者：
Goossens,W
中科院分区：
文献类型：
--
作者：
Eshagian,J;Rafferty,NS;Goossens,W
后囊膜下区的复杂性白内障可能与许多全身疾病有关。对患有视网膜色素变性、特纳综合征、肌强直性营养不良或正在服用皮质类固醇的患者进行白内障囊内摘除术后的临床和病理检查。后囊下混浊主要有两种类型：一种类型有多个空泡，而另一种类型临床表现为更实的（斑块样或雪球样）混浊。空泡性混浊的主要形态对应（光镜和电镜）是液化性坏死伴上皮细胞异常迁移生长到白内障。在斑块样或雪球样混浊中，晶状体纤维通常紊乱成圆形的小球体。临床意义在于，囊外法比斑块样混浊更容易清除后囊下空泡积液性白内障；然而，液泡型的增殖细胞可能是白内障后膜的来源，可能需要分离。
Complicated cataracts of the posterior subcapsular zone may be associated with a number of systemic conditions. Cataracts from patients with retinitis pigmentosa, Turner's syndrome, myotonic dystrophy, or those who were taking corticosteroids were examined clinically and pathologically after intracapsular cataract extraction. Two major types of posterior subcapsular opacities were observed: one type had multiple vacuoles, while the other type was a more solid appearing (plaque-like or snowball) opacity clinically. The predominant morphologic counterpart (by light and electron microscopy) of the vacuolar opacity is liquefactive necrosis with aberrantly migrated epithelial cells growing into the cataract. In the plaque-like or snowball opacity, the lens fibers are generally disorganized into round globules. The clinical significance is that the vacuolar-liquified posterior subcapsular cataract may be more easily removed by extracapsular methods than the plaquelike opacity; however, the proliferative cells in the vacuolar type are probably the source of an after-cataract membrane that may require discission.