Fabrication of a novel glucose biosensor based on a highly electroactive polystyrene/polyaniline/Au nanocomposite
Fabrication of a novel glucose biosensor based on a highly electroactive polystyrene/polyaniline/Au nanocomposite
复制标题
基于高电活性聚苯乙烯/聚苯胺/Au纳米复合材料的新型葡萄糖生物传感器的制备
DOI：
10.1021/jp801938w
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发表时间：
2008-07-31
影响因子：
3.3
通讯作者：
Hou, Wenhua
中科院分区：
文献类型：
--
作者：
Liu, Yuge;Feng, Xiaomiao;Hou, Wenhua
合成了聚苯乙烯（PS）、聚苯胺（PANI）和Au纳米粒子（NPs）的核壳结构纳米复合材料。采用扫描电子显微镜（SEM）、透射电子显微镜（TEM）、X射线衍射（XRD）、X射线光电子能谱（XPS）和傅里叶变换红外光谱（FTIR）对纳米复合材料进行了表征。循环伏安实验表明，该纳米复合材料在较宽的pH值范围内具有良好的氧化还原能力。Au NPs的存在导致纳米复合材料具有更高的电导率。以葡萄糖氧化酶（GOD）为模型，将其固定在纳米复合物修饰的玻碳电极（GCE）上，构建了葡萄糖氧化酶（GOD）传感器。固定化GOD对葡萄糖的氧化有一对清晰的氧化还原峰，并具有较高的催化活性。
A novel nanocomposite with a core-shell structure containing polystyrene (PS), polyaniline (PANI), and Au nanoparticles (NPs) was synthesized. The nanocomposite was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopy (FTIR). Cyclic voltammetric experiments indicated that the nanocomposite had excellent redox ability in a wide range of pH values. The existence of Au NPs resulted in a higher electrical conductivity of the nanocomposite. As a model, glucose oxidase (GOD) was entrapped onto the nanocomposite-modified glassy carbon electrode (GCE) and applied to construct a sensor. The immobilized GOD showed a pair of well-defined redox peaks and high catalytic activity for the oxidation of glucose.