Transcatheter arterial embolization for unruptured renal angiomyolipoma using a 1.8-Fr tip microballoon catheter with a mixture of ethanol and Lipiodol
Transcatheter arterial embolization for unruptured renal angiomyolipoma using a 1.8-Fr tip microballoon catheter with a mixture of ethanol and Lipiodol
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DOI：
10.1186/s42155-019-0095-8
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发表时间：
2020-01-08
影响因子：
1.2
通讯作者：
Hasebe, Terumitsu
中科院分区：
文献类型：
--
作者：
Tomita, Kosuke;Matsumoto, Tomohiro;Hasebe, Terumitsu
目的评价1.8法国尖端微球囊导管和无水乙醇-碘化油混合液经导管动脉栓塞术治疗肾血管平滑肌脂肪瘤的疗效和安全性。在血管平滑肌脂肪瘤供血动脉置入1.8法国尖端微球囊导管，在微球充气下用无水乙醇和碘油的混合物进行动脉栓塞。我们回顾评估了血管肌脂肪瘤的特点、技术成功率、临床成功率、肾功能和不良事件。技术成功和临床成功分别定义为完全栓塞所有供血动脉和缩小肿瘤大小。结果肿瘤平均大小为46 mm(40~64 mm)。经导管动脉栓塞术治疗8例血管平滑肌脂肪瘤均获成功。乙醇和碘油混合液的中位数为6.0ml(2.0~14ml)。乙醇与碘油的比例中位数为71%(范围为71-75%)。所有8个血管肌肉脂肪瘤均缩小，平均直径缩小率为34%(范围9-63%)，体积缩小率为77%(范围48-94%)。中位随访期13个月(9~54个月)。所有病例均取得临床成功。术后血肌酐浓度和肾小球滤过率无明显变化，无严重并发症发生。结论经导管插管插管治疗肾血管平滑肌脂肪瘤安全、有效。
BackgroundTo evaluate the efficacy and safety of transcatheter arterial embolization for renal angiomyolipoma using a 1.8-French tip microballoon catheter and a mixture of ethanol and Lipiodol.MethodsSeven consecutive patients with total of eight angiomyolipomas underwent this procedure between June 2014 and June 2017. A 1.8-French tip microballoon catheter was advanced to the feeding artery of the angiomyolipoma, and transcatheter arterial embolization was performed with a mixture of ethanol and Lipiodol under microballoon inflation. We retrospectively evaluated the characteristics of angiomyolipomas, technical success rate, clinical success rate, renal function, and adverse events. Technical success and clinical success were defined as complete embolization of all feeding arteries and reduction of tumor size, respectively.ResultsThe median size of the angiomyolipomas was 46mm (range, 40-64mm). Transcatheter arterial embolization was successful in all eight angiomyolipomas. The median volume of the mixture of ethanol and Lipiodol was 6.0ml (range, 2.0-14ml). The median ratio of ethanol to Lipiodol was 71% (range, 71-75%). All eight angiomyolipomas shrank with a median shrinkage rate of 34% in diameter (range, 9-63%) and 77% in volume (range, 48-94%). The median follow-up period was 13months (range, 9-54months). Clinical success was achieved in all cases. Serum creatinine concentrations and the pre- and post-procedural estimated glomerular filtration rates did not change notably, and there were no major complications.ConclusionTranscatheter arterial embolization for renal angiomyolipoma using a 1.8-French tip microballoon catheter with a mixture of ethanol and Lipiodol is effective and safe.