Diabetes and cardiovascular disease: changing the focus from glycemic control to improving long-term survival.
Diabetes and cardiovascular disease: changing the focus from glycemic control to improving long-term survival.
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DOI：
10.1016/j.amjcard.2012.08.036
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发表时间：
2012-11-06
影响因子：
2.8
通讯作者：
Reusch, Jane E. B.
中科院分区：
文献类型：
--
作者：
Wang, Cecilia C. Low;Reusch, Jane E. B.
Diabetes is the fifth leading cause of death worldwide and contributes to leading causes of death, cancer and cardiovascular disease including coronary heart disease, stroke, peripheral vascular disease and other vascular disease. While glycemic management remains a cornerstone of diabetes care, the co-management of hypertension, atherosclerosis, cardiovascular risk reduction and prevention of long-term consequences associated with diabetes are now well recognized as essential to improve long-term survival. Clinical trial evidence substantiates the importance of glycemic control, LDL-cholesterol lowering therapy, blood-pressure lowering, control of albuminuria, and comprehensive approaches targeting multiple risk factors to reduce cardiovascular risk. This article presents a review of the role of diabetes in pathogenesis of atherosclerosis and cardiac dysfunction, recent evidence regarding degree of glycemic control and mortality, and available evidence for a multi-faceted approach to improve long-term outcomes for patients.
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