Decreasing HIV, Syphilis, and Hepatitis C Infection After a Decade of Harm Reduction Implementation Among Drug Users in Southwestern Areas of China.
Decreasing HIV, Syphilis, and Hepatitis C Infection After a Decade of Harm Reduction Implementation Among Drug Users in Southwestern Areas of China.
复制标题
中国西南地区吸毒者实施十年减害措施后，艾滋病毒、梅毒和丙型肝炎感染有所减少。
DOI：
10.15288/jsad.2018.79.248
复制
发表时间：
2018-03
影响因子：
3.4
通讯作者：
SIAN HSIANG-TE TSUEI
中科院分区：
文献类型：
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作者：
陈怡;唐振柱;唐帅;沈智勇;朱秋映;李荣健;黄文波;黄玉满;梁富雄;王露;陈欢欢;阮玉华;邵一鸣;蓝光华;SIAN HSIANG-TE TSUEI
目标
自2003年以来，中国中央政府实施了多项减少危害和预防措施来控制艾滋病毒。我们的目的是描述政策实施后广西吸毒者中艾滋病毒、丙型肝炎病毒（HCV）和梅毒的流行病学趋势。
方法
2009年至2015年，中国广西每年通过社区外展或滚雪球抽样的方式招募12,161-15,870名吸毒者。参与者的人口统计、行为和感染状况用于描述保护行为率和疾病流行率（HIV、梅毒和 HCV）。使用卡方趋势检验。
结果
与基线相比，到 2015 年，HIV、HCV 和梅毒的患病率分别从 13.6% 下降到 6.2%、68.0% 下降到 50.5%、8.5% 下降到 5.2%。同时，注射吸毒、共用针头、最后一次无保护性行为和定期无保护性交的比率从 82.6% 下降到 64.5%。分别为24.1%至5.5%、66.6%至39.7%和74.0%至51.2%。从 2009 年到 2009 年，预防服务、美沙酮维持治疗或针头交换、同伴教育计划、上一年艾滋病毒检测以及艾滋病毒状况知识的使用率分别从 63.4% 增加到 93.6%、52.0% 增加到 56.6%、37.4% 增加到 43.1%、45.3% 增加到 91.3%、76.7% 增加到 99.4%。 2015年。
结论
经过十年的艾滋病毒控制政策，这是中国第一项研究表明，随着保护性服务和行为的普及，艾滋病毒、丙型肝炎和梅毒的患病率有所下降。
OBJECTIVE
Since 2003, the Chinese central government has implemented several harm reduction and preventive measures to control HIV. We aim to describe epidemiological trends of HIV, hepatitis C virus (HCV), and syphilis in Guangxi drug users after the policy implementation.
METHOD
A total of 12,161-15,870 drug users in Guangxi, China, were recruited annually from 2009 to 2015 through community outreach or snowball sampling. The participants' demographics, behavior, and infection status were used to characterize rates of protective behaviors and disease prevalence (HIV, syphilis, and HCV). Chi-squared trend testing was used.
RESULTS
Relative to baseline, the prevalence of HIV, HCV, and syphilis decreased from 13.6% to 6.2%, 68.0% to 50.5%, and 8.5% to 5.2%, respectively, by 2015. Concurrently, the rate of injecting drugs, needle sharing, unprotected last sexual encounter, and regular unprotected intercourse decreased from 82.6% to 64.5%, 24.1% to 5.5%, 66.6% to 39.7%, and 74.0% to 51.2%, respectively. The usage of prevention services, methadone maintenance therapy or needle exchange, peer education programs, HIV testing in the previous year, and knowledge of HIV status increased from 63.4% to 93.6%, 52.0% to 56.6%, 37.4% to 43.1%, 45.3% to 91.3%, and 76.7% to 99.4%, respectively, from 2009 to 2015.
CONCLUSIONS
After a decade of HIV control policies, this was the first Chinese study to show a decreasing prevalence of HIV, HCV, and syphilis in the context of increasing uptake of protective services and behaviors.