Strength of the relationship between tobacco smoking, nicotine dependence and the severity of alcohol dependence syndrome criteria in a population-based sample

Strength of the relationship between tobacco smoking, nicotine dependence and the severity of alcohol dependence syndrome criteria in a population-based sample
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DOI:
10.1093/alcalc/agg122
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发表时间:
2003-11-01
影响因子:
2.8
通讯作者:
Hapke, U
Hapke, U
中科院分区:
医学3区
文献类型:
--
作者:
John, U;Meyer, C;Hapke, U

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目的:目前和过去的吸烟行为与酒精依赖的严重程度之间的关系知之甚少。这样做的目的是探索这种关系的力量。方法:随机抽取德国北部18-年龄段的青少年为研究对象(n=4075,参与率:70%)。研究包括761名符合至少一项酒精依赖标准的吸烟者。根据酒精依赖综合征标准频率(ASF),通过基于酒精依赖综合征诊断工具的标准化问卷来评估酒精依赖的严重程度,该问卷包括从从不回答到每天回答的5个类别。尼古丁依赖根据《精神障碍诊断和统计手册》(DSM-IV)和综合国际诊断访谈(CIDI)进行诊断。作为第二个测量,使用了尼古丁依赖的Fagerstrom测试(FTND)。结果:吸烟次数、每日吸烟年限、尼古丁依赖、尼古丁依赖症状数均与ASF有关。卡方检验的效应值(W)为0.17~0.21。在以ASF为因变量(R2=0.17)的一般线性回归模型中,每日吸烟年限、开始吸烟年龄、尝试戒烟或戒烟次数、DSM-IV尼古丁依赖症状个数和FTND总分被保留为自变量。结论:长期吸烟、DSM中的大量尼古丁依赖症状和FTND中的强烈吸烟冲动与高ASF有关。
Aims: Little is known about the relationship between current and past smoking behaviour and the severity of alcohol dependence. The purpose was to explore the strength of this relationship. Methods: A random population sample of 18 to 64 year-olds from northern Germany was used (n = 4075; participation rate: 70%). It included 761 cigarette smokers fulfilling at least one alcohol-dependence criterion. The severity of alcohol dependence according to the alcohol-dependence syndrome criteria frequency (ASF) was estimated by a standardized questionnaire based on diagnostic instruments of the alcohol dependence syndrome and which included five response categories, from 'never' to 'daily'. Nicotine dependence was diagnosed according to the Diagnostic and Statistical Manual of mental disorders (DSM-IV) with the Composite International Diagnostic Interview (CIDI). As a second measure, the Fagerstrom Test of Nicotine Dependence (FTND) was used. Results: The number of cigarettes and years of daily smoking, nicotine dependence, and the number of nicotine dependence symptoms each showed a relationship with the ASF. Effect size (w) were 0.17-0.21 for chi-squared (chi(2)) tests. In a general linear regression model with the ASF as the dependent variable (R-2 = 0.17), number of years of daily smoking, age at onset of smoking, number of attempts to reduce or quit, the number of nicotine-dependence symptoms according to DSM-IV and the FTND sum score were retained as independent variables. Conclusions: Long-term smoking, a large number of nicotine-dependence symptoms according to DSM and a strong urge to smoke according to the FTND are related with a high ASF.