Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge stylotella sp.
Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge stylotella sp.
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DOI：
10.1021/np0704856
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发表时间：
2008-03-01
影响因子：
5.1
通讯作者：
Erickson, Karen L.
中科院分区：
文献类型：
--
作者：
Brennan, Mary R.;Costello, Catherine E.;Erickson, Karen L.
从巴布亚新几内亚海绵柱藻属物种的细胞毒性提取物中分离出一种新的富含脯氨酸的环十肽，命名为柱肽2，并发现其对应于结构1。基于HRMS碰撞诱导解离串联质谱（CID MS/MS）、NMR光谱数据和氨基酸分析进行结构归属，从而确定绝对构型。
A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.