Comparison of Eimeria Species Distribution and Salinomycin Resistance in Commercial Broiler Operations Utilizing Different Coccidiosis Control Strategies
Comparison of Eimeria Species Distribution and Salinomycin Resistance in Commercial Broiler Operations Utilizing Different Coccidiosis Control Strategies
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DOI：
10.1637/9137-111109-reg.1
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发表时间：
2010-09-01
期刊：
影响因子：
1.4
通讯作者：
Fetterer, R.
中科院分区：
文献类型：
--
作者：
Jenkins, M.;Klopp, S.;Fetterer, R.
本研究的目的是评估从商业肉鸡养殖场分离的艾美球虫卵囊的物种组成和盐霉素敏感性，这些养殖场通过球虫病控制（抗球虫药物[ACD]与活卵囊疫苗[VAC]）而不同。艾美耳球虫物种组成和盐霉素敏感性的比较之前和之后，生产商从盐霉素切换到活卵囊疫苗。总体而言，未观察到艾美耳球虫属的浓度存在显著差异。与使用ACD的农场的垃圾相比，使用Vacs的农场的垃圾中的卵囊。应用基于PCR的方法检测球虫发现，从VAC操作的垫料中的艾美球虫物种分布更接近于活卵囊疫苗中的物种组成。药物敏感性试验发现，从VAC操作艾美球虫卵囊显示更大的盐霉素敏感性，通过体重增加和饲料转化效率相比，从ACD农场的卵囊。这些发现提供了额外的证据，活卵囊疫苗的有用性，以恢复在家禽经营的离子载体敏感性，含有艾美耳球虫属的离子载体耐药人口。卵囊
The purpose of the present study was to evaluate the species composition and salinomycin sensitivity of Eimeria oocysts isolated from commercial broiler farms that differed by means of coccidiosis control (anticoccidial drugs [ACD] vs. live oocyst vaccines [VAC]). A comparison of Eimeria species composition and salinomycin sensitivity was also made before and after a producer switched from salinomycin to live oocyst vaccines. In general, no significant difference was observed in the concentration of Eimeria spp. oocysts in litter from VAC-utilizing farms compared to litter from ACD-utilizing farms. Application of PCR-based methods to detect coccidia found that Eimeria species distribution in litter from VAC operations more closely resembled the species composition in the live oocyst vaccines. Drug sensitivity testing found that Eimeria oocysts from VAC operations displayed greater salinomycin sensitivity as measured by weight gain and feed conversion efficiency compared to oocysts from ACD farms. These findings provide additional evidence for the usefulness of live oocyst vaccines to restore ionophore sensitivity in poultry operations that contain an ionophore-resistant population of Eimeria spp. oocysts.