IMPROVED TECHNIC FOR CANINE LUNG TRANSPLANTATION
IMPROVED TECHNIC FOR CANINE LUNG TRANSPLANTATION
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DOI：
10.1097/00000658-197004000-00012
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发表时间：
1970-01-01
影响因子：
9
通讯作者：
RICHARDS, K
中科院分区：
文献类型：
--
作者：
VEITH, FJ;RICHARDS, K
方法：移植技术。体重超过15公斤的狗。尽管该方法在小至7公斤的动物身上成功地进行过。在预期的受体动物中，通过第五肋间隙进行标准的左胸切开术。下肺韧带是分开的。将左肺动脉从第一分支至起始处剥离，去除所有动脉外膜。在肺动脉主动脉上打开心包，在肺动脉主动脉上的内脏心包反射上放置夹钳。在该钳的外侧和前方牵引有助于右侧肺动脉主干的剥离（图1）。这条血管广泛的后上方暴露，可以进行周向剥离，并用结扎术包围。然后将心包切口向下延伸，露出左心房前部和引流右肺大膈叶的右下肺静脉（图1）。通过在左下肺叶上施加牵引力，可以直接显露左主干支气管和左心房之间的无血管平面。后支气管剥离仅限于前神经胸膜的分离。除了暴露右肺动脉外，在供体肺上进行类似的解剖，其大小应与受体肺相当或略大。配对的直钳或斜钳放置在左肺动脉-553上
Methods Technic of Transplantation. Dogs weighing more than 15 Kg. were used although the procedure has been performed successfully in animals as small as 7 Kg. In the prospective recipient animal, a standard left thoracotomy is performed through the fifth intercostal space. The inferior pulmo-nary ligament is divided. The left pulmo-nary artery is dissected free of all adven-titia from its first branch to its origin. The pericardium is opened over the main pul-monary artery and a clamp is placed on the visceral pericardial reflection overlying the main pulmonary artery. Traction on this clamp laterally and anteriorly facilitates dissection of the right main pulmonary artery (Fig. 1). Extensive posterior and superior exposure of this vessel permits circumferential dissection and encirclement with a ligature. The pericardial incision is then extended inferiorly exposing the anterior aspect of the left atrium and the right inferior pulmonary vein which drains the large diaphragmatic lobe of the right lung (Fig. 1). By traction exerted superiorly on the left lower lobe, it is possible to develop bluntly the avascular plane between the left mainstem bronchus and the left atrium. The posterior bronchial dissection is limited to division of the vis-ceral pleura. With the exception of exposure of theright pulmonary artery, a simi-lar dissection is carried out on the donor lung which should be of a comparable size or slightly larger than that of the recipient. Paired straight or angled atraumatic clamps are placed across the left pulmo-553