An allenic Pauson-Khand-type reaction:: A reversal in π-bond selectivity and the formation of seven-membered rings
An allenic Pauson-Khand-type reaction:: A reversal in π-bond selectivity and the formation of seven-membered rings
复制标题
DOI：
10.1021/ol025955w
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发表时间：
2002-05-30
期刊：
影响因子：
5.2
通讯作者：
Geib, SJ
中科院分区：
文献类型：
--
作者：
Brummond, KM;Chen, HF;Geib, SJ
[图]用[Rh(CO)(2)Cl](2)处理炔基烯，形成正式的[2 + 2 + 1]环加成反应。该反应对多种底物具有完全的区域选择性，只产生4-烷基烯环戊烯酮，收率高。此外，七元环的制备也取得了高产率。
[GRAPHICS]Treatment of alkynyl allenes with [Rh(CO)(2)Cl](2) results in a formal [2 + 2 + 1] cycloaddition reaction. This reaction occurs with complete regioselectivity for a variety of substrates affording only 4-alkylidene cyclopentenones in good yields. Moreover, seven-membered rings have been prepared in high yields.